摘要
目的了解复方克痛宁的术后镇痛疗效。方法通过前瞻性研究,采用随机抽表双盲法观察复方克痛宁对47例术后中重度疼痛病人的治疗效果,及其安全性,并以45例用盐酸哌替啶者做对照。结果复方克痛宁对术后中重度疼痛的缓解率为9361%,镇痛效果与盐酸哌替啶相似,但镇痛时间明显长于盐酸哌替啶,用药中未发现不良反应,也未发现对机体肝肾功能、免疫功能方面的损害。结论复方克痛宁止痛效果优良,安全性好,服用方便,有望成为替代盐酸哌替啶的术后镇痛药物。
Objective By premonitory research,using randomly and two-blind sampling,the efficiency and security of the compound KeTongNing and pethidine hydrochloride had been compared.Methods 47 cases of violent pain after surgery showed that KeTongNing had similar effect with pethidine hydrochloride.Results The effective rate of palliation is 93 61%,but KeTongNing had longer action time.No side-effects such as damage to liver or kidney function had been observed.Conclusion Compound KeTongNing is a good new analgesic medicine without side-effects,easy to take,could be a substitution to pethidine hyrochloride for surgery.
出处
《中国实用外科杂志》
CSCD
北大核心
1999年第4期217-219,共3页
Chinese Journal of Practical Surgery
关键词
镇痛药
复方克痛宁
手术后
疼痛
Analgesic medicine\ KeTongNing\ Violent pain after surgery