摘要
目的:比较不同医疗保健体系老年2型糖尿病患者降糖药应用的合理性及有效性。方法:采用横断面、现场调查方法,收集2009年在我院就诊的108名老年2型糖尿病干部患者,及北京某社区随诊的98名老年2型糖尿病患者降血糖药物的治疗模式、费用及血糖控制达标情况,分析比较两组人群降糖药治疗模式的合理性及有效性。结果:二甲双胍和阿卡波糖分别为老干部组和社区组约半数患者的主要降血糖药物。按照《中国2型糖尿病防治指南》控制标准,老干部组空腹血糖(FBG)、糖化血红蛋白(HbA1c)达标率分别为64.8%和41.7%,高于社区组(分别为11.2%和30.6%)。老干部组总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)的达标率也明显高于社区组。老干部组日均降糖药费用高于社区组,日均降糖药费用在10元以内的老干部组占46.3%、社区组占73.5%。联合2种或2种以上降糖药治疗的老干部组占66.7%,社区组占53.1%。社区组仍有少数患者应用格列苯脲和苯乙双胍。结论:两组老年患者降糖药物应用模式基本相近,老干部组用药合理性优于社区组,血糖、血脂各项控制达标率也高于社区组,可能与老干部组更多联合用药和降糖药费用较高有关。
Objective： To compare the rationality and effectiveness of hypoglycemic agents in elderly type 2 diabetic patients in different health care systems. Methods： Using cross-sectional and field survey methods, the hypoglycemic drug treatment patterns, costs and target blood glucose control of elderly type 2 diabetic patients were collected, among whom 108 patients were treated in our hospital （the veteran group） and 98 patients were followed up in a community in Beijing （the community group） in 2009. The rationality and effectiveness of hypoglycemic drug treatment patterns in these two groups were compared. Results： Metformin and acarbose were the major hypoglycemic drugs, which were used in about half of patients in the veteran group and community group. According to the diabetic control standards of ＇Chinese Type 2 Diabetes Prevention Guide＇, the proportions of the patients whose fasting blood glucose （FBG） and glycosylated hemoglobin （HbA1c） were controlled well in the veteran group were 64.8% and 41.7%, higher than that of the community group （11.2% and 30.6%）. The control rate of total cholesterol （TC）, triglyceride （TG）, low-density lipoprotein （LDL-C） and high-density lipoprotein （HDL-C） in the veteran group were also signif icantly higher than that of the community group. The average daily costs of hypoglycemic agents in 46.3% of the veteran group and in 73.5% of the community group were less than 10 yuan. The proportions of combination of two or more than two kinds of hypoglycemic medication were 66.7% in the veteran group and 53.1% in the community group. A small number of patients in community group still took glibenclamide and phenformin. Conclusion： The hypoglycemic drug treatment patterns of two groups were basically similar. The rationality of drug usage in the veteran group was superior to that in the community group, and the control rates of the indexes in blood glucose and lipid were higher in the veteran group than in the community group, which may re
出处
《中国药物应用与监测》
CAS
2010年第4期216-219,共4页
Chinese Journal of Drug Application and Monitoring
基金
全军医药卫生科研基金课题(07BJZ03)
关键词
2型糖尿病
降糖药
老年患者
药物治疗
合理性
有效性
Type 2 diabetes mellitus
Hypoglycemic agent
Elderly patient
Drug therapy
Rationality
Effectiveness
