摘要
目的采用超声二维斑点追踪技术(STE)评价心脏再同步化治疗(CRT)后患者的左心房功能,探讨其临床应用价值。方法接受CRT的心力衰竭患者49例,在术前3天及术后3个月应用Simpson法计算左心房被动射血分数(LA-PEF)和主动射血分数(LAAEF),采用STE检测左心房侧壁及房间隔收缩期应变率(SRs-LA、SRs-IAS)、舒张早期应变率(SRe-LA、SRe-IAS)、舒张晚期应变率(SRa-LA、SRa-IAS),同时测量左心室收缩末容积(LVESV)和射血分数(LVEF)。将术后LVESV减小率(ΔLVESV)≥15%定义为CRT短期治疗有效。结果 CRT术后3个月的27例患者(55.10%)CRT短期治疗有效(R组)。术前R组患者的所有参数与无效患者比较差异无统计学意义,术后参数与无效患者比较,R组患者的LVESV减小,LVEF增大,LAPEF、LAAEF增加,SRs-LA、SRe-LA、SRa-LA、SRs-IAS、SRe-IAS、SRa-IAS明显增加(P均<0.05)。结论 CRT短期可明显改善左心房功能;STE能准确评价左心房功能。
Objective To evaluate the impact on left atrial function with two-dimensional speckle tracking echocardiography （STE） in patients after cardiac resynchronization therapy （CRT）. Methods Forty-nine heart failure patients scheduled for CRT were included. STE was performed 3 days before and 3 months after the pacemaker implantation. Left atrial passive ejection fraction （LAPEF） and left atrial active ejection fraction （LAAEF） were calculated with Simpson method. Peak systolic stain rate （SRs-LA, SRs-IAS）, peak early diastolic stain rate （SRe-LA, SRe-IAS） and peak late diastolic strain rate （SRa-LA, SRa-IAS） on the interatrial septum and the lateral wall of the left atrium using speckle tracking echocardiography were analyzed. LV end-systolic volume （LVESV） and left ventricular ejection fraction （LVEF） were also measured. Patients were divided into responders and non-responders, based on a reduction ≥15% in LVESV after CRT. Results Twenty-seven patients （55.10%） were classified as responders. Compared with non-responders, there was no difference in preoperative state, while the responders demonstrated a significant increase of LVEF, LAPEF, LAAEF, SRs-LA, SRs-IAs, SRe-LA, SRe-IAs, SRa-LA, SRa-IAs on the interatrial septum and the lateral wall of the left atrium, and LVESV decreased （all P0.05）. Conclusion CRT can promptly increase the left atrial function. STE are readily obtained parameters that provide unique data about atrial function.
出处
《中国医学影像技术》
CSCD
北大核心
2010年第9期1704-1707,共4页
Chinese Journal of Medical Imaging Technology
基金
辽宁省自然科学基金(20082106)
辽宁省教育厅科学技术研究基金(2008748)
