摘要
目的:观察针刺辨证治疗中风后抑郁症的临床疗效。方法:300例中风后抑郁症患者随机分为针刺组150例(以"四神针"为主穴,配合中医证候分型取穴,每日1次)及氟西汀组150例(口服氟西汀每日20mg),两组疗程均为2个月。分别在治疗前后用汉密尔顿抑郁量表(HAMD)对两组患者进行评定,统计两组疗效,并对疗效与证型的关系进行分析。结果:治疗后,两组的HAMD评分均较治疗前明显下降(P<0.05);针刺组HAMD的评分优于氟西汀组(P<0.05)。针刺组总有效率为89.3%(134/150),氟西汀组总有效率为76.0%(114/150),两组比较差异有统计学意义(P<0.05)。针刺组各证型的疗效也均优于氟西汀组(均P<0.05)。结论:针刺辨证治疗中风后抑郁症疗效较好。
Objective To observe the clinical therapeutic effect of acupuncture in the treatment of post-stroke depression (PSD) in the light of syndrome differentiation. Methods A total of 300 PSD patients were randomized into acupuncture group and medication group,with 150 cases in each group. For patients of acupuncture group,Sishencong (EX-HN1), Baihui (GV 20), Shenting (GV 24), etc. were punctured combined with other acupoints according to different syndromes, once daily for 2 months. For patients of medication group,fluoxetine (20 mg/d) was administered orally,continuously for 2 months. Hamilton's depression scale (HAMD) was used to evaluate changes of PSD patients' state after the treatment. Results After the treatment, the scores of HAMD in both groups decreased significantly (P〈0.05), and that of acupuncture group was remarkably lower than that of medication group (P〈0.05). Of the two 150 PSD patients in medication and acupuncture groups, 35 (23.3%) and 16 (10.7%) cases were cured, 82(54.7%) and 41(27.3%)had a marked improvement, 17(11.3%) and 57(38.0%) had an im- provement,and 16( 10.7% ) and 36(24.0% ) were ineffective,with the total effective rates being 89.3% and 76.0% respectively. Chi-square test showed that the therapeutic effect of acupuncture was significantly superior to that of medication group (P〈0.05). Conclusion Acupuncture is effective in improving post-stroke depression in PSD patients.
出处
《针刺研究》
CAS
CSCD
北大核心
2010年第4期303-306,共4页
Acupuncture Research
关键词
针刺
中风后抑郁症
氟西汀
Acupuncture therapy
Post-stroke depression
Fluoxetine