摘要
目的探讨异种脱细胞神经桥接大鼠面神经缺损后的神经再生方式。方法用脱细胞兔面神经作为移植物桥接大鼠面神经颊支2 cm缺损,以自体腓神经移植作为正常对照组。术后5周和12周,取面神经移植段中部及远端吻合口处各3mm神经组织,进行组织学检测。结果 12周时,两组中移植段分叉处远端均有再生纤维,再生纤维数在两组之间无显著性差异。结论异种脱细胞神经作为神经再生通道,其再生能力与自体神经无显著差异,可以作为自体神经移植的可选替代物。
Objective To discuss the nerve regeneration of facial nerve defect with acellular heterogeneous nerve transplant.Methods 36 Wistar rats were experimental animals.2 cm facial nerve defects were repaired by acellular rabbit facial nerve.At the same time,their own sural nerves were transplanted as control side.5,12 weeks after the operation,we selected 3 mm nerve in the middle and outlyings part to observe the histological changes.Results There was regenerated nerve fibre in the middle and outlying parts in the two groups.And there were no differences between two groups.Conclusions Heterogeneous acellular nerve transplant can be a kind of favorable nerve choice,and its regeneraion capability has no distinct difference from that of autotransplant.
出处
《口腔医学》
CAS
2010年第8期449-451,共3页
Stomatology
基金
国家自然科学基金资助项目(30872898)
解放总医院创新基金资助项目(06ZS13)
关键词
异种脱细胞神经
神经移植
面神经缺损
acellular heterogeneous nerve
nerve transplant
facial nerve defect
