摘要
目的评价西比灵治疗偏头痛的疗效及治疗前后的经颅多普勒改变。方法 88例偏头痛患者随机分为治疗组和对照组,西比灵组予西比灵5mg,qn,两组均连续服药4周为1个疗程,2个疗程时间间隔3天,2个疗程后评定疗效,并在治疗前后有经颅多普勒(TCD)检测大脑前动脉(ACA)、大脑中动脉(MCA)、大脑后动脉(PCA)及基底动脉(BA)的血流速度。结果西比灵组头痛消失时间随每次发作而缩短,与对照组比较有显著性差异(P>0.01);治疗组治疗后,平均流速明显降低,与治疗前比较有非常显著性差异(P<0.01);对照组无显著性差异(P<0.05)。结论西比灵能改善脑血流的供应,为偏头痛的治疗提供了依据。
Objective To evaluate the effect and change of the pre-and-post treatment for migraine with transcranial doppler by the use of sibelium.Methods 88 patients with migraine were randomly chosen and put into the treatment group and the control group who received a dosage of 5 mg sibelium qn.The two groups took the medicine successively for 4 weeks which was taken as a curse of treatment.The interval of every 2 courses was 3 days.An evaluation of the treatment was carried out after 2 courses.Results There was a sharp difference（P0.01） in the time of a headache disappearance for the treatment group.After the treatment,the average blood flow of the treatment group decreased greatly and was significantly different from that before the treatment while blood flow of the control group showed a humble diffenence（P0.05）.Conclusion Sibelium cauld improve cerebral blood supply and provided the basis for treatment of migraine.
出处
《佛山科学技术学院学报（自然科学版）》
CAS
2010年第3期79-82,共4页
Journal of Foshan University(Natural Science Edition)
关键词
西比灵
偏头痛
多普勒
血流速度
sibelium
migraine
transcranical doppler
blood flow velocity
