摘要
目的：研究Gd-EOB-DTPA显示胆管系统的能力与特性,比较Gd-EOB-DTPA增强磁共振胆管成像（EOB-MRC）与磁共振胆胰管成像（MRCP）的胆管系统结构显示情况。方法：16例肝占位且未侵犯胆管系统的病例资料纳入研究。所有患者均先行MRCP扫描和抑脂3D GRE T1WI（VIBE）扫描,注射Gd-EOB-DTPA后约30min行抑脂3DVIBE胆管成像。统计Gd-EOB-DTPA增强前后抑脂3D VIBE胆管信号变化、胆管-肝脏对比噪声比（CNR）绝对值变化和EOB-MRC、MRCP及两者结合胆管系统结构显示的评分情况。结果：Gd-EOB-DTPA增强前和增强后30min胆总管信号强度分别为113.27±38.20和595.31±34.62,胆囊信号强度分别为182.73±113.45和684.20±153.41;胆总管-肝脏CNR绝对值分别为131.13±33.29和86.56±48.44,胆囊-肝脏CNR绝对值分别为105.91±45.96和125.59±50.45;Gd-EOB-DTPA增强前后胆总管和胆囊内的信号强度之间差异有显著性意义（P〈0.001）,Gd-EOB-DTPA增强前后胆总管-肝脏CNR绝对值差异有显著性意义（P〈0.001）,胆囊-肝脏CNR绝对值变化差异无统计学意义（P〉0.05）。胆管系统结构显示情况评分：EOB-MRC与MRCP对胆总管、肝总管、左右肝管及胆囊管的显示大致相仿,EOB-MRC与MRCP结合时评分高于前两者,但三者间差异均无统计学意义（P〉0.05）;胆囊的可见度EOB-MRC评分为3.09±1.00,低于MRCP的评分（3.76±0.44）,两者结合评分为3.82±0.39,三项评分差异存在统计学意义（P〈0.01）;肝内二级胆管的可见度EOB-MRC评分为2.25±1.33,高于MRCP的评分（1.67±1.33）,但差异无统计学意义,EOB-MRC与MRCP两者结合时肝内二级胆管的可见度评分最高,有2.59±1.22。结论：Gd-EOB-DTPA增强磁共振胆管成像可以满意显示胆管系统,与MRCP互为补充,两者联合应用可进一步提高胆管系统显示,并有望了解胆管系统功能状况。
Objective：To evaluate the ability and characteristics of Gd-EOB-DTPA in depicting biliary structures and to compare the degree of biliary visualization of Gd-EOB-DTPA-enhanced magnetic resonance cholangiography （EOB-MRC） with magnetic resonance cholangiopancreatography （MRCP）.Methods：16 patients （male 15,female 1） with known hepatic masses but without invasion of biliary system were enrolled in the study.All patients underwent MRCP and precontrast 3D GRE T1WI （3D VIBE） with fat suppression,EOB-MRC using 3D VIBE with fat suppression was done 30 minutes after Gd-EOB-DTPA injection.Signal intensity of liver parenchyma,intra-common bile duct （CBD） and intra-gallbladder （GB） as well as absolute value of contrast to noise ratios （CNR） of duct-liver were quantitatively analyzed pre and post contrast.Biliary visualization of EOB-MRC and MRCP was qualitatively assessed by using a Likert 5-point scale respectively and paired.Results：Signal intensity in the common bile duct before and 30 minutes after Gd-EOB-DTPA injection was 113.27±38.20 and 595.31±34.62 while 182.73±113.45 and 684.20±153.41 in the gallbladder.At the same time, absolute value of CBD-liver CNR was 131.13±33.29 and 86.56±48.44 while 105.91±45.96 and 125.59±50.45 of GB-liver.There were significant differences in signal intensities and absolute value of CBD-liver CNR between precontrast and after injection （P〈0.001）,for absolute value of GB-liver CNR,there was no statistically significant difference （P〉0.05）.Visualization rating of common bile duct,common hepatic duct,left hepatic duct and right hepatic duct using EOB-MRC and MRCP had no statistically significant difference,the rating was improved by using paired of MRCP and EOB-MRC,but there were also no statistically significant differences among paired and unpaired.Visualization rating of gallbladder for EOB-MRC and MRCP was 3.09±1.00 and 3.76±0.44,paired was 3.82±0.39,showed statistically significant difference （P〈0.01）.For sub-branches of int
出处
《放射学实践》
北大核心
2010年第8期872-876,共5页
Radiologic Practice
关键词
钆DTPA
磁共振成像
胆管成像
对比剂
Gadolinium DTPA
Magnetic resonance imaging
Cholangiography
Contrast media
