摘要
目的:为临床治疗药物致胰岛素自身免疫综合征(IAS)提供参考。方法:分析我院药物所致IAS1例,综合我国已经报道的药物致IAS的临床资料进行分析。结果:我国药物致IAS病例中,在病因和临床表现方面,与国外报道的IAS的发病特点一致,但其年龄却低于国外IAS总体发病人群;在治疗方面,国内大部分的IAS患者采用了糖皮质激素的治疗,与日本报道的资料存在明显的差异。结论:IAS病情多为严重,故在临床工作中遇到自发性低血糖患者应充分了解其用药史,注意鉴别,减少因误诊和漏诊给患者带来的痛苦和死亡风险。
OBJECTIVE： To provide reference for the treatment of drug-induced insulin autoimmune syndrome （IAS）. METHODS： One drug-induced IAS case reported in our hospital was analyzed, combining with clinical information of reported drug-induced IAS cases in China. RESULTS： Of reported drug-induced IAS cases in China, those etiology and symptoms were correspond with the characteristics of foreign reported IAS cases; patients’ age was lower than the average age of IAS patients; IAS patients were mostly treated with glucocorticoid in China, which is significantly different from reported cases in Japan. CONCLUSION： Most IAS patients are in serious condition. In clinical practice pharmacists should fully understand the medication history of patients with spontaneous hypoglycemia, and identify the difference between IAS and spontaneous hypoglycemia carefully to reduce the pain and risk of death for patients resulted from misdiagnosis and missed diagnosis.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第32期3031-3032,共2页
China Pharmacy
关键词
胰岛素自身免疫综合征
中国人
自发性低血糖
Insulin autoimmune syndrome
Chinese population
Spontaneous hypoglycemia
