摘要
目的观察0.25%左旋布比卡因重比重腰麻-硬膜外联合麻醉(combin spinal anesthesiaepidural anesehesia,CSEA)用于剖宫产术的麻醉效果及可行性.方法选择ASAⅠ～Ⅱ级100例于CSEA下择期及急诊行剖宫产术的患者,随机双盲法分为两组:L组(n=50)和B组,L组注入0.25%左旋布比卡因重比重液3mL,B组注入0.25%盐酸布比卡因重比重液3mL,调整麻醉平面上界至T6～T9水平,监测呼吸和循环情况,评价麻醉效应及不良反应发生情况.结果两组在注药后最初10min内循环变化有统计学意义,且B组较L组变化更为明显(P<0.05),镇痛和肌松效果两组比较无统计学意义(P>0.05),两组不良反应发生情况无统计学意义(P>0.05).结论 0.25%左旋布比卡因重比重CSEA较0.25%盐酸布比卡因重比重CSEA用于剖宫产术更安全有效.
Objective To observe the effects and feasibility of 0.25% levobupivacaine spinal anesthesia-epidural anesthesia（CSEA）for cesarean section.Methods According to randomized double-blind method,100 ASA I～II patients who received elective and emergent cesarean section under CSEA were divided into two groups：L group （n=50）and B group （n=50）.Patients in L group were injected with 0.25% levobupivacaine 3 mL,and patients in B group were injected with 0.25% bupivacaine hydrochloride 3 mL.We adjusted the anesthesia community to the chest plane 6-Chest 9 levels,monitored respiration and circulation,and evaluated anesthetic effects and adverse reactions.Results There was a significant difference in circulation changes within 10 minutes after injection of anesthetics between the two groups,and the circulation changes in B group were more significant than in L group（P〈0.05）.There was no significant difference in analgesic and muscle relaxant effect,and the incidence of adverse reactions between the two groups（P〉0.05）.Conclusion Compared with 0.25% bupivacaine hydrochloride CSEA,0.25% levobupivacaine CSEA for cesarean section is safer and more effective.
出处
《昆明医学院学报》
2010年第7期40-42,共3页
Journal of Kunming Medical College
