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疼痛治疗在细胞水平的研究进展 被引量:7

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摘要 传统的药物止痛有诸多不可避免的缺陷。目前,细胞水平的镇痛治疗、基因治疗、免疫源内源性镇痛在动物试验研究方面获得了大量的资料和经验,取得了突破性的进展。这些研究成果为我们提供了新的疼痛治疗手段,并为临床应用奠定了基础。
出处 《中国疼痛医学杂志》 CAS CSCD 北大核心 2005年第5期302-304,共3页 Chinese Journal of Pain Medicine
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参考文献17

  • 1Eaton MJ. Emerging cell and molecular strategies for the study and treatment of painful peripheral neuropathies. JPNS, 2000, 5: 60 ~ 73. 被引量:1
  • 2Unsicker K. The trophic cocktail made by adrenal chromaffin cells. Exp Neurology, 1993,123 : 167~ 173. 被引量:1
  • 3卢中平,江伟,徐惠芳.疼痛分子治疗的研究进展[J].国外医学(麻醉学与复苏分册),2004,25(2):71-74. 被引量:3
  • 4Czech KA, Ryan JW, Sagen J, et al. The influence of xenotransplant immunogenicity and immunosuppression on host MHC expression in the rat CNS. Exp Neurology, 1997, 147: 66~83. 被引量:1
  • 5安珂,杨辉,田玉科.生物细胞的永生化和去永生化在细胞镇痛中的应用进展[J].国外医学(麻醉学与复苏分册),2004,25(2):65-67. 被引量:1
  • 6Russ AP, Friedel C, Ggrez M, et al. Self-deleting retrovirus vector for gene therapy. J Virol, 1996,70: 4927 ~ 4932. 被引量:1
  • 7Eaton M J, Heman JP, Julien N, et al. Immortalized chromaffin cells disimmortalized with Cre-Lox site-directed recombination for use in cell therapy for pain after nerve injury. Exp Neurol, 2002, 175: 49 ~ 60. 被引量:1
  • 8Yao MZ, Gu JF, Wang JH, et al. Interleukin-2gene therapy of chronic neuropathic pain. Neuroscience, 2002,112:409 ~416. 被引量:1
  • 9Goss JR, Mata M, Goins WF, et al. Antinociceptive effect of a genomic herpes simplex virus-based vector expressing human proenkephalin in rat dorsal root ganglion. GENE THERAPY, 2001, 8 :551 ~ 556. 被引量:1
  • 10Eaton MJ, Blits B, Ruitenberg MJ, et al. Amelioration of chronic neuropathic pain after partial nerve injury by adeno-associated viral (AAV)vector-mediated over-expression of BDNF in the rat spinal cord., GENE THERAPY ,2002, 9 :1387 ~ 1395. 被引量:1

二级参考文献58

  • 1Eaton MJ, Herman JP, Jullien N, et al. Immortalized chromaffin cells disimmortalized with Cre/Lox site-directed recombination for use in cell therapy for pain after partial nerve injury. Exp Neurol, 2002,175:49-60. 被引量:1
  • 2Sagen J, Pappas GD, Perlow MJ. Adrenal medullar transplants in the rat spinal cord reduce pain sensitivity. Brain Res, 1986,384:189-194. 被引量:1
  • 3Anton M, Graham FL. Site-specific recombination mediated by an adenovirus vector expressing the Crc recombinase protein: a molecular switch for control of gene expression. J Virol, 1995,69:4600-4606. 被引量:1
  • 4Berghella L, De Angelis L, Coletta M, et al. Reversible immortalization of human myogenic cells by site-specific excision of a retrovirally transferred oncogene. Hum Gene Ther, 1999,10:1607-1617. 被引量:1
  • 5Kobayashi NT, Fujiwara KA, Westerman Y, et al. Prevention of acute liver failure in rats with reversibly immortalized human hepatocytes. Science,2000,287:1258-1262. 被引量:1
  • 6Lakso M, Sauer B, Mosinger B, et al. Targeted oncogene activation by sitespecific recombination in transgenic mice. Proc Natl Acad Sci USA, 1992,89: 6232-6236. 被引量:1
  • 7Shockett PE, Schatz DG. Diverse strategies for tetracycline-regulated inducible gene expression. Proc Natl Acad Sci USA, 1996,93:5173-5176. 被引量:1
  • 8Brocard J, Warot X, Wendling O, et al. Spatio-temporally controlled sitespecific somatic mutagenesis in the mouse. Proc Natl Aced Sci USA, 1997,94:14559-14563. 被引量:1
  • 9Kellendonk C, Tronche F, Casanova E, et al. Inducible site-specific recombination in the brain. J Mol Biol, 1999,285:175-182. 被引量:1
  • 10Russ AP, Friedel C, Ggrez M, et al. Self-deleting retrovirus vector for gene therapy. J Virol, 1996,70: 4927-4932. 被引量:1

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