摘要
目的 结合1例颈静脉孔异位垂体腺瘤患者的临床资料,探讨异位垂体腺瘤的发生机制、临床、病理特点及治疗方法.方法 回顾性分析1例颈静脉孔异位垂体腺瘤患者的临床资料.本患者临床表现为左耳耳鸣及间断性枕部疼痛,无内分泌功能紊乱症状,头颅MRI示左侧颈静脉孔区不规则椭圆形肿瘤影像,稍长T1、稍长T2信号,边界尚清楚,周边可见囊变,信号欠均匀,增强扫描病变不均匀强化.结果 行左侧乙状窦后入路,显微镜下全切除肿瘤,术后恢复顺利,病理回报ACTH型垂体腺瘤.术后化验ACTH值为23.7 pg/ml,其他内分泌指标均正常.结论 异位于颈静脉孔的垂体腺瘤少见,术后病理是诊断的主要依据,手术治疗效果好,如有内分泌功能紊乱症状在给予手术治疗的同时,可合理选择放疗和药物治疗.
Objective To explore the mechanism, clinical manifestation, pathological features, diagnosis and treatment of jugular foramen ectopic pituitary adenoma. Method The clinical data of a patient with jugular foramen ectopic pituitary adenoma were analyzed retrospectively. The clinical features were tinnitus of the left ear and headache. There was no endocrine disturbance. MR1 showed a long Tl, long T2 lesion with clear boundary in jugular foramen. The axial contrast - enhanced Tl - weighted image was non -uniform. Results The tumor was dissected under microscope through suboccipital retrosigmoidal approach. Postoperative recovery was well Pathological examination showed an adenoma with pituitary cells,and the endocrine examination showed that ACTH was 23.7pg/ml and others was normal. Conclusions Pituitary adenoma ectopic to jugular foramen was seldom. Its clinical features were disorder of neural function and endocrine disturbance. Its diagnosis mainly depends on pathological examination. Treatment strategy should be depended on the location and the classification of the endocrine types. The prognosis of operation is good. Total removal is recommended for its treatment Radiotherapy and drug treatment should be considered after surgery.
出处
《中华神经外科杂志》
CSCD
北大核心
2010年第7期596-598,共3页
Chinese Journal of Neurosurgery
基金
基金项目：首都医科大学基础与临床科研合作基金（2006GL53）
首都医学发展科研基金（2005-3-519）
关键词
垂体腺瘤
异位
颈静脉孔
诊断
治疗
Pituitary adenoma
Ectopic
Jugular foramen
Diagnosis
Treatment
