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肿瘤相关成纤维细胞研究进展 被引量:5

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摘要 人类肿瘤的90%来源于上皮组织,上皮细胞需要在生长信号的不断作用下避免分化和凋亡,获得无限复制的潜能,并依靠新生血管生成、获得侵袭、转移能力才能最终形成肿瘤。整个过程依赖于肿瘤细胞与宿主间质微环境的相互作用,遗传学和细胞生物学研究表明,间质细胞可以提供肿瘤细胞生长、增殖信号,并参与新生血管生成,
出处 《癌症进展》 2010年第4期380-383,共4页 Oncology Progress
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同被引文献100

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