摘要
目的:探讨高海拔地区原发性高血压合并红细胞增多症患者心脏重构的特点。方法:236例住院高血压患者按是否合并红细胞增多症分为红细胞正常组和红细胞增多症组,比较两组年龄、病程、移居高原时间、血压水平、心脏结构的变化以及心脏重构的发生率。结果:红细胞增多症组患者年龄水平小于红细胞正常组[(50.39±13.77):(57.30±12.13)岁](P<0.05),舒张压水平高于红细胞正常组[(103.51±13.30):(97.14±15.26)mmHg(1mmHg=0.133kPa)](P<0.05)。红细胞增多症组患者右心房左右径、右室舒张末内径、右室流出道、左心房前后径、舒张末室间隔厚度和舒张末左室后壁厚度,与红细胞正常组比较明显增大[(39.16±6.31):(34.15±5.44)mm、(38.85±7.71):(33.96±5.09)mm、(25.83±4.67):(23.36±2.35)mm、(34.11±4.56):(32.25±5.60)mm、(12.88±1.67):(12.03±1.83)mm和(12.29±1.75):(10.88±1.65)mm](均P<0.05)。红细胞增多症组患者右心房扩大、右心室扩大和左室肥厚罹患率显著高于红细胞正常组(24.6%:8.4%、27.5%:9.0%和79.7%:58.1%)(均P<0.05);而左心房和左心室扩大的罹患率在2组间比较差异无统计学意义(P>0.05)。结论:在高海拔地区原发性高血压合并红细胞增多症患者心脏重构特点以右心系统改变更显著。
Objective：To investigate the characteristic of cardiac remodeling in patients with essential hypertension （EH） and polycythemia in high altitude.Method：A total of 236 in-patients was categorized into 2 groups：EH with polycythema group （69 cases）,and EH with normal erythrocyte group （167 cases）.The differences of two groups on the blood pressure,cardiac structure,prevalence of cardiac enlargement and left ventricular hypertrophy （LVH） were compared.Result：In the EH with polycythemia group,the DBP,LA,IVS,LVPW,RA and RV increased significantly compared with those in normal erythrocyte group[（103.51±13.30）mmHg vs （97.14±15.26） mmHg,（34.11±4.56）mm vs （32.25±5.60）mm,（12.88±1.67）mm vs （12.03±1.83）mm,（12.29±1.75）mm vs （10.88±1.65）mm,（39.16±6.31）mm vs （34.15±5.44）mm and （38.85±7.71）mm vs （33.96±5.09）mm] （all P0.05）] respectively;furthermore,the prevalence of right atrium enlargement,right ventricula enlargement and left ventricular hypertrophy in EH with polycythemia group increased significantly compared with those in normal erythrocyte group （24.6% vs 8.4%、27.5% vs 9.0% and 79.7% vs 58.1%）.Conclusion：The enlarge of right atrium and right ventricle are distinctive in patients with EH and polycythemia in high altitude.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2010年第6期433-435,共3页
Journal of Clinical Cardiology
关键词
高血压
红细胞增多症
高海拔
心室重构
hypertension
polycythemia
altitude
ventricular remodeling
