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异基因造血干细胞移植后肺部并发症的临床观察 被引量:3

Clinical observation of pulmonary complications after allogenentic hematopoietic stem cell transplantation
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摘要 目的观察血液病异基因造血干细胞移植(allo-HSCT)后肺部并发症。方法对本科2007年1月至2009年12月134例异基因造血干细胞移植患者进行回顾性分析。结果 134例患者中37例出现肺部并发症,发生率为27.6%,死亡14例。结论肺部并发症是异基因造血干细胞移植的常见并发症,其中感染性肺部并发症占主要,死亡率高。肺部并发症的发生率与预后是与患者和供者的人类白细胞抗原(HLA)配型相合程度、患者的年龄相关。 Objective To investigate allogenetic hematopoietic stem cell transplantation pulmonary complications.Methods My Section from January 2007 to December 2009 134 routine allogeneic hematopoietic stem cell transplant patients were analyzed retrospectively.Results Showed that:In 134 patients,37 patients had pulmonary complications,the incidence rate was 27.6%,of which 14 patients died.Conclusion Pulmonary complications is allogeneic hematopoietic stem cell transplantation a common complication,which accounts for the main infectious pulmonary complications and high mortality.The incidence of pulmonary complications and prognosis of patients and donors with the HLA-type coincide with the degree of patient′s age was significantly related.
出处 《重庆医学》 CAS CSCD 北大核心 2010年第14期1846-1847,共2页 Chongqing medicine
关键词 异基因造血干细胞移植 肺部并发症 allogeneic hematopoietic stem cell transplantation pulmonary complications
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参考文献3

  • 1Soubani AO,Miller KB,Hassoun PM.Pulmonary complications of bone marrow transplantation[J].Chest,1996,109(4):1066. 被引量:1
  • 2Duncker C,Dohr D,Harsdorf S,et al.Non-infectious lung complications are closely associated with chronic graft-versus-host disease:a single center study of incidence,risk factors and outcome[J].Bone MarrowTransplant,2000,25(12):1263. 被引量:1
  • 3马巧玲,冯四洲,王枚,魏嘉璘,杨栋林,闫章松,何祎,李新,刘宏,韩明哲.异基因造血干细胞移植后肺部并发症的发生和危险因素分析[J].生物医学工程与临床,2007,11(2):129-133. 被引量:5

二级参考文献9

  • 1Soubani AO,Miller KB,Hassoun PM.Pulmonary complications of bone marrow transplantation[J].Chest,1996,109 (4):1066-1077. 被引量:1
  • 2Duncker C,Dohr D,Harsdorf S,et al.Non-infectious lung complications are closely associated with chronic graft-versus-host disease:a single center study of incidence,risk factors and outcome[J].Bone Marrow Transplant,2000,25 (12):1263-1268. 被引量:1
  • 3Mohty M,Bilger K,Jourdan E,et al.Higher doses of CD34+ peripheral blood stem cells are associated with increased mortality from chronic graft-versus-host disease after allogeneic HLA-ientical sibling transplantation[J].Leukemia,2003,17(8):1467-1469. 被引量:1
  • 4Patriarca F,Skert C,Sperotto A,et al.Incidence,outcome,and risk factors of late-onset noninfectious pulmonary complications after unrelated donor stem cell transplantation[J].Bone Marrow Transplant,2004,33 (7):751-758. 被引量:1
  • 5O'Brien SN,Blijlevens NM,Mahfouz TH,et al.Infections in patients with hematological cancer:recent developments[J].Hematology Am Soc Hematol Educ Program,2003,(2):438-472. 被引量:1
  • 6Ninin E,Milpied N,Moreau P,et al.Longitudinal study of bacterial,viral,and fungal infections in adult recipients of bone marrow transplant[J].Clin Infect Dis,2001,33(1):41-47. 被引量:1
  • 7Wakayama M,Shibuya K,Ando T,et al.Deep-seated mycosis as a cormplication in bone marrow transplantation patients[J].Mycoses,2002,45(5-6):146-151. 被引量:1
  • 8Winston DJ,Maziarz RT,Chandrasekar PH,et al.Intravenous and oral itraconazole versus intravenous and oral fluconazole for long-term antifungal prophylaxis in allogeneic hematopoietic stem-cell transplant recipients.A multicenter,randomized trial[J].Ann Intern Med,2003,138(9):705-713. 被引量:1
  • 9Marr KA,Crippa F,Leisenring W,et al.Itraconazole versus fluconazole for prevention of fungal infection in patients receiving allogeneic stem cell transplants[J].Blood,2004,103 (4):1527-1533. 被引量:1

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