摘要
以丙醛和甲醛为原料，经缩合及氧化２步反应，合成了２，２二羟甲基丙酸。缩合反应在４０℃、甲醛与丙醛摩尔比为２．５∶１、三乙胺用量为原料质量的３％的条件下反应１０ｈ，氧化反应在９５℃、过氧化氢与丙醛摩尔比为１．１∶１的条件下反应７ｈ，获得了最佳反应结果，产品总收率５２．２％，纯度９８％。
The α,α dimethylolpropionic acid was made from propylaldehyde and formaldehyde followed by reaction with condensation and oxidation.A study of the effects on the synthesis was done,which gave the optimum conditions that the condensation reaction was run at 40℃ for 10h with 2.5∶1 molar ratio of formaldehyde to propylaldehyde and the triethylamine is 3% of feedstock,the oxidation reaction was run at 95℃ for 7h with 1.1∶1 molar ratio of hydrogen peroxide to propylaldehyde.The total yield is 52.2% with the product purity of 98%.
出处
《精细化工》
EI
CAS
CSCD
北大核心
1999年第1期28-31,共4页
Fine Chemicals
关键词
二羟甲基丙酸
缩合
氧化
α,α dimethylolpropionic acid
condensation
oxidation
