摘要
目的:探讨血浆脑钠素(BNP)对急性心肌梗死(AMI)患者早期诊断的临床意义。方法:采用酶联免疫吸附(ELISA)方法测定AMI患者入院当时及24h的血浆BNP水平,以健康人为对照,比较各组间BNP的差异。结果:AMI组BNP血浆水平在24h内显著增高(1469.40±346.56),与对照组(32.93±0.42)比较差异有显著性意义(P<0.001);AMI组患者入院当时BNP血浆水平(1432.40±335.36)与24h时(1469.40±346.56)相比无显著性差异(P>0.05)。结论:AMI患者的血浆BNP值明显升高,对AMI的早期诊断有重要意义。
Objective： To explore the clinical significance of brain natriuretic peptide （BNP） detec- tion in early diagnosis of acute myocardial infarction （AMI）. Methods： The plasma brain natriuretic pep- tide （BNP） levels of 38 AMI patients were measured by enzyme-linked immunosorbent assay （ELISA） at 0 h and 24 h after admission, and were compared with normal levels in healthy control participants. Results： No significant different plasma BNP levels was found between AMI patients and healthy control participants at admission（1 432.40±335.36 vs 1 469.40±346.56,P〉0.05） while 24 h after admission plas- ma BNP was obviously increased in AMI patients, significantly higher than that of healthy control partici- pants（1469.40±346.56 vs32.93±0.42, P〈0.001）. Conclusions：The level of BNP was significantlyin- creased in AMI patients, showing predictive value for the early diagnosis of AMI.
出处
《海南医学院学报》
CAS
2010年第7期847-848,852,共3页
Journal of Hainan Medical University
基金
海南省自然科学基金项目(808234)~~
关键词
急性心肌梗死
脑钠素
免取免疫吸附测定
Acute myocardial infarction
Brain natriuretic peptide
Enzyme-linked immunosorbent assay
