摘要
目的 探讨老年胃食管反流病（GERD）患者的临床特征,为临床诊断、治疗提供帮助.方法 根据GERD蒙特利尔的标准、中国胃食管反流病共识意见等,将GERD患者分为老年组（年龄≥65岁）与中青年组（年龄＜65岁）;通过问卷调查,分析2组GERD患者的食管裂孔疝（HH）、食管炎（洛杉矶标准）、临床症状（反流、烧心等）、生活质量.结果 两组性别比差异无统计学意义（P＞0.05）.与中青年GERD患者比较：老年患者重度食管炎（LC级＋LD级）比例高（P＜0.05）;典型反酸、烧心症状轻（P＜0.05）,食管外症状发生率高（P＜0.05）;但HH发生率差异无统计学意义（P＞0.05）.老年患者生理功能、总体健康、活力、社会功能、精神健康、躯体生理健康总评和精神心理健康总评积分与年轻组差异无统计学意义（P＞0.05）,仅生理职能、躯体疼痛、情感职能积分较中青年组高（P＜0.05）.结论 老年GERD患者典型反流症状（反食、烧心）较少见,易发生重度食管炎,但老年GERD患者生活质量无明显下降.
Objective To analyze clinical characteristics of gastroesophageal reflux disease（GERD） in aged patients for improvement of diagnosis and treatemcnt. Methods The reflux disease questionnaire was performed in patients diagnosed as GERD based on Montreal definition and classification as well as Rome Ⅲ criteria.All patients were divided into elderly group （≥65 years） and control group（〈65 years）. The incidence of hita[ hernia （HH）, the frequencies of esophagitis （based on Los Angeles classification）, clinical features, and quality of life were compared between two groups. Results There was no difference between two groups in male/female ratio and morbidity of HH（P〉0.05）. In comparison with control group, the frequency of esophagitis graded as LC or LD increased and extra-esophageal symptoms were higher in elderly group （P〈 0.05）, but the lower typical symptoms （heartburn and regurgitation） were seen in the elderly group（P〈0.05）. The scores of role physical, bodily pain and role emotional were higher in elderly group than those in control group （P〈0.05）. There was no significant differences between two groups in physical function, vitality,social functioning, mental health, and general health. Conclusion The elderly GERD patients often have lower score of typical reflux symptoms （heartburn and regurgitation） and high incidence of severer esophagitis, but their quality of life is not significantly influenced.
出处
《中华消化杂志》
CAS
CSCD
北大核心
2010年第6期382-385,共4页
Chinese Journal of Digestion
基金
基金项目：江苏省自然科学基金（BK2008466）
关键词
胃食管反流
老年人
食管炎
生活质量
Gastroesophageal
Aged
Esophagitis reflux
Quality of life
