摘要
目的分析综合干预对老年血糖调节异常(IGR)患者进展为糖尿病的情况。方法对177例老年IGR患者(干预组)的生活方式进行4年综合干预,同期选择55例不进行综合干预的IGR患者作为对照组,分析空腹血糖受损、糖耐量异常患者进展为糖尿病的情况。结果干预组患者空腹血糖受损、糖耐量异常、空腹血糖受损合并糖耐量异常进展为糖尿病的比率分别为17.14%、20.99%和42.31%,空腹血糖受损合并糖耐量异常进展为糖尿病的比率分别是空腹血糖受损、糖耐量异常的2.47、2.02倍。与对照组比较,干预组空腹血糖受损、糖耐量异常患者进展为糖尿病的比率分别减少了55.01%和52.77%(P<0.05,P<0.01)。结论综合干预能有效控制与消弱心血管疾病危险因素,阻止或延缓IGR患者进展为糖尿病。
Objective To analyse influence of comprehensive intervention on progression from impaired glucose regulation（IGR） to diabetes in elderly patients. Methods Comprehensive intervention on lifestyle, hypertension, dyslipidemia, body mass index and follow-up for four years were conducted in 177 old IGR patients（group Ⅰ ）,and 55 old IGR patients served as control group. According to the new criteria of impaired fasting glucose（IFG）, the progression rate from IFG and impaired glucose tolerance（IGT） to diabetes was analyzed. Results After 4 years,in group Ⅰ ,the progression rates of IFG, IGT, and IFG-IGT were 17. 14%, 20. 99%, 42.31% respectively. The progression rate from IFG-IGT to diabetes was 2.47,2.02 times the rate of progression from simple IFG and simple IGT respectively. Compared with control group, the rates of progression to diabetes from IFG and IGT reduced by 55. 01%, 52.77% （P 〈 0.05,P 〈 0. 01） respectively in group Ⅰ. Conclusion Comprehensive intervention can effectively control some risk factors for cardiovascular disease and prevent or delay progression from IGR to diabetes.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2010年第6期523-525,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金
总后卫生部保健局资助课题(B2000)
关键词
糖尿病
糖尿病前期
葡糖耐量试验
干预性研究
危险因素
diabetes millitus
prediabetic state
glucose tolerance test
intervetion studies
risk factors
