摘要
目的探讨晚期卵巢浆乳癌病人血清CA-125检测与血小板(PLT)计数增高之间的关系。方法收集2002年1月～2008年12月在中国医科大学附属第一医院收治的晚期卵巢浆乳癌46例。其中,Ⅲ期44例,Ⅳ期2例,并以同期收治的卵巢浆乳瘤61例为对照。采空腹静脉血测定PLT计数及CA-125。结果晚期卵巢浆乳癌与浆液性囊腺瘤病人中CA-125检测及PLT计数之间差异均有显著性(P<0.01)。PLT计数>300×109个/L病人共20例,该部分病人CA-125检测结果明显高于PLT正常者。两者之间的差异有显著性(P<0.05)。同时,在PLT增高的病人中,完成满意减瘤术的比例低于PLT正常者,两者之间的差异也有显著性。结论 PLT增高可能成为晚期卵巢浆乳癌预后不良的因素之一。
[Objective] To study the incidence of thrombocytosis in women with advanced ovarian serous cystadenomcarcinoma as compared to benign controls consisting of ovarian serous cystadenoma and together with serum CA125 to correlate it with primary surgical treatment.[Methods]Hospital records of 46 patients with ovarian serous cystadenomcarcinoma （44 patients had stage III and 2 patients had stage IV disease）, and of 61 patients with ovarian serous cystadenoma were reviewed. The clinical data , preoperative serum CA125 and platelet counts were recorded. [Results] The incidence of thrombocytosis in advanced ovarian serous cystadenomcarcinoma was significantly higher than in benign controls （P 0.01）. Statistically significant correlation was found between thrombocytosis with the serum CA125 （P 0.05）. The patients with thrombocytosis have significantly less favorable rate of ideal cytoreductive surgery （P 0.05）. [Conclusion]Thrombocytosis is significantly more prevalence in ovarian cancer patients than in benign controls and has a statistically significant correlation with the rate of ideal cytoreductive surgery. This implies that thrombocytosis is probably a marker of ovarian cancer prognosis.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2010年第10期1575-1577,共3页
China Journal of Modern Medicine
关键词
腺癌
卵巢
血小板
CA-125
预后
adenocarcinoma
ovary
thrombocytosis
CA-125
prognosis
