摘要
目的研究腰椎穿刺脑脊液置换术治疗重型颅脑损伤伴蛛网膜下腔出血的临床治疗效果。方法将符合重型颅脑损伤伴蛛网膜下腔出血诊断标准的病例,按对照原则设计实验组与对照组各34例,在常规抢救治疗基础上,实验组加腰椎穿刺脑脊液置换术治疗,对照组未行腰椎穿刺脑脊液置换术,其他治疗措施完全相同,比较两组疗效。结果实验组栓溶二聚体(DIM)明显低于对照组,差异有统计学意义(P<0.05);脑梗死发生率实验组为12%、对照组为29%;脑积水发生率实验组为15%、对照组为32%;预后良好率:实验组为29%、对照为12%,中残率:实验组为18%、对照组为9%;病死率:实验组24%、对照组为50%,差异有统计学意义(P<0.05)。结论腰椎穿刺脑脊液置换术治疗重型颅脑损伤伴蛛网膜下腔出血,方法简单,效果肯定,能提高治愈率,减少病死率。
Objective To study the clinical effect of the lumbar puncture cerebrospinal fluid replacement treats severe traumatic brain injury with subarachnoid hemorrhage. Methods The patients were consistent with severe traumatic brain injury diagnostic criteria of subarachnoid hemorrhage. There were 34 cases respectively,divided into experimental group and control group by control rules. Up on the route rescue treatment, experimental group were treated by lumbar puncture cerebrospinal fluid replacement, and the control group bad no lumbar puncture cerebrospinal fluid replacement surgery,and other treatment measures were exactly the same. Compared the effects. Results Suppository dissolved dimer （DIM） of the experimental group were significantly lower than the control group,and there were statistics differences （P〈0.05）. The rate of cerebral infarction of the experimental group was 12% and the control group was 29%. The incidence of hydrocephalus of the experimental group was 15.% and the control group was 32%. Good Prognosis rate of the experimental group was 29% and the control group was 12%. The disabled rate of the experi- mental group was 18% and the control group was 90%. The mortality of the experimental group was 24% and control group was 50%,a significant difference between the two groups （P〈0. 05）. Conclusion lumbar puncture eerebrospinal fluid replacement for the treatment of severe brain injury with subarachnoid hemorrhage which is simple and effective can improve the cure rate and re- duce mortality.
出处
《重庆医学》
CAS
CSCD
北大核心
2010年第13期1679-1680,共2页
Chongqing medicine
关键词
重型颅脑损伤
腰椎穿刺脑脊液置换术
治疗
病死率
severe traumatic brain injury
lumbar puncture cerebrospinal fluid replacement
treat
mortality
