摘要
目的探讨德莫林对大白鼠烫伤模型的治疗效果。方法采用随机,自身同体对照的试验方法,Wistar雄性大白鼠,体重(250±50)g,在鼠背部制成对称深Ⅱ度烧伤创面,面积约10%TBSA。治疗组创面用1g/100cm2德莫林治疗,对照组创面常规涂抹磺胺嘧啶银霜。观察治疗5、7、10、14、18d时创面皮肤的愈合情况及愈合率。结果治疗组创面肉芽组织增生的时间明显早于对照组创面,治疗组创面伤后5、7、10、14、18d时的愈合率明显高于对照组创面(P<0.05)。结论德莫林对烧伤创面的愈合有明显促进作用。
Objective To investigate the burned rat model of demoline therapeutic effect.Methods A randomized,self-control with the body of the test method,Wistar male rats,body weight（250±50）g,in the mouse back into the deep symmetry Ⅱ degree burn wounds,an area of about 10% TBSA.Treatment group with 1g/100cm2 demoline wound treatment,control group of conventional wound sulfadiazine coated Ag Cream.5、7、10、14、18d treatment of skin wound healing and the healing rate.Results The treatment group wound granulation tissue hyperplasia significantly wound back in the control group,treatment group,5、7、10、14、18d after injury,wound healing,when the rate was significantly higher than that wound（P0.05）.Conclusion The burn wounds on demoline significant role in promoting healing.
出处
《四川医学》
CAS
2010年第6期712-713,共2页
Sichuan Medical Journal
