摘要
目的了解双黄连注射剂严重不良反应/事件发生的相关因素,为临床用药提供参考。方法对2004年1月～2009年6月湖南省药品不良反应监测中心收到的7例静脉滴注双黄连注射剂致死的不良反应报表进行统计分析。结果 7例双黄连注射剂致死的严重不良反应全部发生在基层卫生机构,其中有6例死于过敏性休克。14岁以下年龄组的有3例(占42.86%),所占比例最高。结论临床应合理使用双黄连注射剂,并加强用药监护,以减少严重不良反应的发生。
[Objective]The related factors of severe adverse drug reaction（ADR）cases caused by Shuanghuanglian injection are analyzed to provide the reference for clinical appliance. [Methods]7 cases fatal adverse drug reactions collected by Hunan Center for ADRs from January 2004 to June 2009 were statistically analyzed. [Results]7 cases fatal adverse drug reactions took place at primary level medical establishment, in which 6 cases fatal adverse drug reactions were caused by anaphylactic shock. 3 cases fatal adverse drug reactions occurred the age below 14 years old, with the highest proportion.[Conclusion]Shuanghuanglian should be rational used in clinical practice with strongly monitoring to reduce fatal adverse drug reactions.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2010年第11期1704-1707,共4页
China Journal of Modern Medicine
