摘要
介绍了近年来4种阿韦莫哌的合成方法,以及其中间体的4种合成方法,并评述了各种方法的优缺点。这些方法主要是把阿韦莫哌分成了2个模块,分别对模块进行合成与拼接。并在分析现有工艺的基础上,提出了一条可能的路线:分别以间溴苯甲醚和苯丙烯酸甲酯为起始原料制备模块1与模块2,然后反应直接得到产品。
4 synthesis methods of mopipe and 4 synthesis methods of its intermediates are introduced,their advantages and disadvantages are reviewed.These methods mainly divide mopipe into two modules which are synthesized and put together.On the base of analysis,a possible route is put forward.m-Bromophenyl methyl ether and cinnaldehyde are used as raw materials for the preparation of module 1 and module 2,followed by reaction to get the product directly.
出处
《化工生产与技术》
CAS
2010年第3期27-32,共6页
Chemical Production and Technology
