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浅析运动性免疫抑制的几种生理机制 被引量:6

Physiological mechanisms of exercise-induced immune suppression
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摘要 不适宜运动后免疫系统功能低下是一种常见的现象,但具体生理机制有待于进一步探讨。目前认为大强度或大运动量的运动后免疫细胞数量的降低或功能的减退、血浆中儿茶酚胺骤减、皮质醇逐渐增加至峰值、血浆中促炎性因子(TNF-α、IL-1β)的含量不变或稍增加而抗炎性因子(IL-6、IL-1ra、TNF-ar、IL-10)显著增加、免疫细胞细胞膜表面受体(HR、TLR、IL-2R、CXCR4)及粘附分子表达下调等,均是导致运动性免疫抑制重要因素。 It is common that immune system suppression can take place after high tensity strenuous exercise, but the concrete mechanisms need further study. It is now acknowleded that the number and function changes of immune cells, the amounts of hormens endocrine system produces such as catecholamine, cortisol, cell factors and adhesive molecules ex- pression may all plays important role in the immune system supression.
出处 《山东体育学院学报》 CSSCI 北大核心 2010年第6期40-46,共7页 Journal of Shandong Sport University
基金 山东省自然科学项目(项目编号:Y2003C01)
关键词 运动性免疫抑制 IL-6 Toll-样受体 exercise - induced immune suppression IL - 6 toll - like receptor
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