摘要
目的调查十堰地区恶性肿瘤患者的隐孢子虫感染情况及流行特点,为恶性肿瘤患者隐孢子虫感染的防治提供依据。方法采集十堰市太和医院217例恶性肿瘤患者粪便,采用金胺酚+改良抗酸染色法检查隐孢子虫卵囊。结果 217例肿瘤患者隐孢子虫感染率为48.85%,男性患者与女性患者隐孢子虫感染率分别为49.58%和47.96%,差异无统计学意义(P>0.05);化疗、放疗、化疗+放疗患者隐孢子虫感染率分别为38.46%、37.88%和69.86%,差异有统计学意义(P<0.01);不同类别的肿瘤患者的隐孢子虫感染率分别是:呼吸系统为37.50%、消化系统为60.78%、乳腺为38.89%、其他(包括脑瘤、肾上腺瘤、甲状腺瘤等)为40.00%,差异有统计学意义(P<0.01)。结论恶性肿瘤患者易发生隐孢子虫感染,可能与其机体的免疫功能下降有关。
Objective To explore the prevalence and epidemiological characteristic of Cryptosporidium infection among malignant tumor patients,and to provide evidence for prevention and control of Cryptosporidiosis. Methods Stool specimens of 217 patients were collected. Oocysts of cryptosporidium were identified with auramine phenol staining and modified anti-acid staining. Results The total positive infection rate of Cryptosporidium was 48.85%. There was no significant difference in male and females infection rates （49.58% vs 47.96%）. The infection rate in chemotherapy,radiotherapy and combined therapy was 38.46%,37.88% and 69.86%,respectively,and there were significant deviation in the rates between chemotherapy and other treatments （P0.01）. The infection rates in cancer patients of respiratory system,digestive system,lacteal gland and others （including cerebroma,suprarenoma and thyroid adenoma etc.） were 37.50%,60.78% ,38.89% and 40.00% ,respectively,and there were also significant deviation among different category patients （P0.01）. Conclusion Malignant tumor patients are susceptible to Cryptosporidium infection. This manifests is probably due to depression of immunity.
出处
《热带医学杂志》
CAS
2010年第5期553-554,569,共3页
Journal of Tropical Medicine
关键词
恶性肿瘤患者
隐孢子虫
感染
malignant tumor patient
Cryptosporidium
infection
