摘要
目的:研究观察阿托伐他汀治疗慢性心力衰竭的临床疗效。方法:选择确诊的慢性心力衰竭患者80例,随机分成两组,阿托伐他汀组40例和常规治疗组40例。阿托伐他汀组在常规治疗基础上加用阿托伐他汀(20mg/日),共治疗6个月,对照组接受常规抗心力衰竭治疗,治疗前后观察患者症状、体征、日常生活自理情况等,复查血脂、C反应蛋白、左室射血分数。结果:阿托伐他汀组C反应蛋白均明显下降,差异具有统计学意义(P<0.05)。阿托伐他汀组心功能参数(左心室射血分数)改变较常规治疗组明显(P<0.05)。结论:阿托伐他汀对慢性心力衰竭患者的治疗有良好作用,且能明显改善心功能。
Objective：The effects of atorvastatin used in the chronic heart failure（CHF）were studied in the article.Methods：A retrospective review was performed among 80 patients who chronic heart failure.The patients with CHF were divided into two groups：atorvastatin group （n=40）and conventional treatment group （n=40）.The patients in the atorvastatin group were given conventional medication of anti-heart failure;while those in the conventional treatment group were given additional Atorvastatin 20mg each day, treated for 6 months.Before and after treatment,To observed in patients with symptoms,signs,activities of daily living conditions and so on,review blood lipids,C-reactive protein（CRP）,left ventricular ejection fraction.Results：The results were that the CRP of atorvastatin group were decreased with significant difference（P〈0.05）,Atorvastatin group of cardiac function parameters （left ventricular ejection fraction） to change than the conventional treatment group was significantly（P0.05）.Conclusion：The conclusions were that the cardiac functional of CHF patients were improved by added atorvastatin therapy.
