摘要
目的：研究荨麻科苎麻属植物苎麻叶的化学成分。方法：利用95%的乙醇室温浸提,运用硅胶柱色谱、Sephadex LH-20及半制备HPLC方法进行分离纯化,根据理化性质及各种波谱方法鉴定其化学结构。结果：从石油醚、乙酸乙酯及正丁醇萃取部位分离并鉴定了7个化合物,分别为kiwiionoside（1）,eugenyl β-rutinoside（2）,尿嘧啶（3）,胡萝卜苷（4）,3-羟基-4-甲氧基苯甲酸（5）,胆甾醇（6）,α-香树脂醇（7）。结论：化合物1~3,5~7为首次从苎麻属植物分离得到。
Objective：To study the chemical constituents from the leaves of Boehmeria nivea.Method：The leaves were extracted by 95% EtOH at room temprature,the chemical leaves were isolated and purified by repeated silica gel column chromatography,Sephadex LH-20 column chromatography and semipreparative HPLC,and their structures were identified by physical and chemical properties and spectroscpoic methods.Result：One compound isolated from n-butanol fraction,four compounds were obtained from ethyl acetate fraction and three compounds from petroleum ether fraction.Their structures were elucidated as kiwiionoside（1）,eugenyl β-rutinoside（2）,uracil（3）,β-sitosterol glucoside（4）,3-hydroxy-4-methoxy-benzoic acid（5）,cholesterol（6）,α-amyrin（7）.nonacosanol（8）.Conclusion：Compounds 1-3,5-8 were isolated from the genus Boehmeria for the first time.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2010年第11期1432-1434,共3页
China Journal of Chinese Materia Medica
基金
水利部水土保持植物开发研究中心科技专项(SDH20088080
SDH20088190)
湖北省自然科学基金创新群体计划(2007ABC008)
