摘要
目的了解我院药品不良反应(ADR)发生特点及引发的相关因素,为临床合理用药及药物安全性评价提供依据。方法对我院2008年收集到的152例ADR报告进行统计分析。结果 152例ADR报告中,女性患者明显多于男性,男女之比为1∶1.57;60岁以上(含60岁)的老年人为ADR的高发人群;抗微生物类药物引起的ADR居首位,其次为中药注射剂;ADR的临床表现以皮肤系统损害最为常见;而给药方式以静脉滴注引发ADR的概率最高(占71.71%)。结论临床应高度重视老年人的合理用药及不良反应监测,合理使用抗微生物类药物,加强对中药注射剂的质量监控,减少或避免不良反应的重复发生。
Objective To understand the occurrence features and relevant inducement of adverse drug reactions（ADR） occurred at our hospital to provide foundation for rational clinical use of drug and drug safety evaluation.Methods T ADR reports of 152 cases collected at our hospital in year 2008 was analyzed statsitically.Results Among the 152 cases,there were significantly more female patients than male;and the ration of male to female was 1∶1.57.Patients of 60 years old are high-risk population of ADR;ADR caused by anti-microbial drugs comes first;followed by ADR caused by traditional Chinese medicine injections;Damage to the skin appears to happen the most frequently among all ADR clinical manifestations;and ADR initiated by intravenous dripping occupies the highest probability with 71.71%.Conclusion The clinical staffs should pay more attention to rational use of drug on old people as well as to monitoring of adverse reaction.In addition,we should properly utilize anti-microbial drugs and enhance quality control of traditional Chinese medicine injection so that the recurrence of ADR could be reduced or even avoided.
出处
《中国全科医学》
CAS
CSCD
北大核心
2010年第16期1802-1804,共3页
Chinese General Practice
关键词
药品不良反应
合理用药
Adverse drug reaction
Rational use of drug
