摘要
目的促进临床合理用药。方法采用回顾性调查方法,对医院2008年收集到的67份药品不良反应(ADR)报表进行统计分析。结果67例ADR患者中,女性ADR发生率是男性的1.58倍;中老年患者(≥50岁)发生ADR的几率更大(64.18%);抗微生物类药物引起的ADR最多(70.15%),其中绝大多数是由喹诺酮类和头孢菌素类引发,其次为中药制剂;静脉滴注给药方式是导致ADR的主要途径(92.54%);临床表现以皮肤及其附件损害最常见(34.33%),其次为消化系统反应(22.39%)。结论应继续加强ADR的监测和上报工作,促进临床合理用药。
Objective To promote the rational drug use in clinic. Methods A total of 67 adverse drug reaction（ADR） cases collected by our hospital in 2008 were analyzed retrospectively and statistically in terms of patients＇ age, sex, drug categories, routes of administration and clinical manifestations. Results Of the total 67 cases, the majority （61.19%） were female which was 1.58 times of male. The elderly patients（≥50 years） showed the higher proportion （64. 18% ） of ADR（70. 15% ） were induced by antimicrobial drugs, and the vast majority were from quinolones and cephalosporins, followed by the traditional Chinese medicine 92.54% were induced by intravenous route,34. 33% presented with lesions of skin and its appendices, followed by digestive system reaction. Conclusion We should continue to strengthen the monitoring and reporting work in order to promote the rational drug use.
出处
《中国药业》
CAS
2009年第16期58-59,共2页
China Pharmaceuticals
关键词
药品不良反应
回顾性分析
合理用药
adverse drug reaction（ADR）
retrospective analysis
rational drug use
