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小剂量肝素治疗小儿全身炎症反应综合征临床研究

Clinical research of small--dose heparin to treat systemic inflammatory response syndrome in infants
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摘要 目的:探讨小剂量肝素治疗小儿全身反应综合征的临床效果。方法:选择80例SIRS患儿,随机分为观察组和对照组,对照组常规方法治疗,观察组在此基础上加用小剂量肝素,比较两组疗效和不良反应。结果:观察组治疗总有效率为90%,对照组治疗总有效率为60%,两组比较差异有统计学意义(P〈0.05);观察组不良反应发生率为20%,对照组为17.5%,两组比较无显著差异(P〉0.05)。结论:小剂量肝素治疗小儿全身炎症反应综合征疗效显著,值得在临床推广应用。 Objective: to explore the clinical effect of small--dose heparin to treat systemic inflammatory response syndrome in infants. Method: select 80 SIRS infants and randomly divided into observation group and control group, the control group were treated with traditional method and the observation group were add treated with small--dose heparin, compare their treat effect and complication. Results: the total effect of observation is 99%, which of the control group is 60%, the difference is statistical signifieant(P〈0.05) ; complication rate of the observation group is 20%, which of the control group is 17.5%, the difference is not ohvious(P〉0.05). Conclusion: it is good effect to treat SRIS with small--dose heparin and can be widely use in clinic.
作者 曾品芳
出处 《医学信息(下旬刊)》 2010年第6期21-22,共2页 Medical information
关键词 肝素 全身炎症反应综合征 小儿 heparin systemic inflammatory response syndrome infants
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  • 1Jones H, Paul W, Page CP. The effects of heparin and related molecules on vascular permeability and neutrophil accumulation in rabbit skin[J]. Br J Pharmacol, 2002, 135 (2): 469-479. 被引量:1
  • 2Welty-wolf KE, Carraway MS, Miller DL, et al. Coagulation blockade prevents sepsis-induced respiratory and renal failure in baboons[J].Am J Respir Crit Care Med, 2001,164:1988-1996. 被引量:1
  • 3Warren BL, Eid A, Singer P, et al. Caring for the critically ill patient. High dose antithromin III in severe sepsis:a randomized controlled trial [J].J Am Med Assoc, 2001,286:1869-1878. 被引量:1
  • 4Abraham E, Reinhart K, Opal S, et al. Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis[J]. J Am Ned Assoc, 2003, 290: 238-247. 被引量:1
  • 5Members of American College of Chest Physician/Society of Critical Care Medicine Consensus Conference Commitee. Definition for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis [J]. Crit Care Med, 1992, 20:864-874. 被引量:1
  • 6Kinasewitz GT, Yan SB, Basson B, et al. Universal changes in biomarkers of coagulation and inflammation occur in pateints with sever sepsis ,regardless of causative micro-organism [J]. Critcal Care, 2004, 8:R82-90. 被引量:1
  • 7Bernard GR, Vincent JL, Laterre PF,et al. Efficacy and sa human activated p ment of patients fety of recombinated rotein C for treatsever sepsis [J]. N Engl J Med, 2001, 344: 699-709. 被引量:1
  • 8Stephan F, Hollande J, Richard Q, et al. Thrombocytopenia in a surgical ICU [J]. Chest, 1999, 115:1363-1370. 被引量:1
  • 9Warkentin TE, Levine MN, Hirsh J, et al. Heparin-induced thrombocytopenia in patients treated with loww-molecular-weight heparin or unfractionated heparin[J]. N Engl J Ned, 1995,332:1330-1335. 被引量:1
  • 10Vervloet M;Thijs L;Hack C.Derangements of coagulation and fibrinolysis in critically ill patients with sepsis and septic shock[J],1998(1). 被引量:2

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