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磁共振新技术评估阿尔茨海默病脑内铁沉积 被引量：4

Novel MRI techniques in evaluating brain iron deposition in Alzheimer＇s disease
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摘要 越来越多的研究证明阿尔茨海默病（AD）有脑内铁的代谢紊乱、脑铁沉积增加,且脑内铁的过量沉积与氧化应激及β淀粉样变密切相关,与AD的发生和病情的进展关系密切。MRI可以无创性地检查脑内铁的变化,因而对AD的发病机制、早期诊断及动态监测病情变化具有重要价值。就目前所采用的AD脑铁测量的各种MRI序列及其优缺点进行综述,并介绍尚未应用于AD的定量测量脑铁的新技术。
作者 李思瑶 何慧瑾
机构地区 复旦大学附属华山医院放射科
出处 《国际医学放射学杂志》 2010年第1期6-9,共4页 International Journal of Medical Radiology
关键词 阿尔茨海默病 脑内铁沉积 磁共振成像 脑铁测量
分类号 R742.04 [医药卫生—神经病学与精神病学]
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参考文献26

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同被引文献28

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国际医学放射学杂志
2010年 第1期

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