摘要
心血管疾病是导致2型糖尿病患者死亡的主要原因,本文概括地讨论了胰升糖素样肽1(GLP-1)对内皮功能、缺血性心肌损伤和心衰的保护作用,以及长效GLP-1类似物利拉鲁肽对体重、血压和血脂等心血管危险因素的改善作用。
Cardiovascular disease is the main cause of death in patients with type 2 diabetes. The protection of glucagon-like peptide-1 (GLP-1) on endothelial function, ischemic myocardial damage, and heart failure have been reviewed. Based on the recently finished serial clinical studies, the effects that long-acting GLP- 1 analogues liraglutide improved body weight, blood pressure, lipids, and other cardiovascular risk factors were discussed.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2010年第5期437-440,共4页
Chinese Journal of Endocrinology and Metabolism
关键词
胰升糖素样肽1
心血管疾病
利拉鲁肽
糖尿病
2型
Glucagon-like peptide-1
Cardiovascular disease
Liraglutide
Diabetes mellitus, type 2