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促性腺激素使用天数对体外授精-胚胎移植及妊娠结局的影响 被引量:2

Impact of duration of gonadotropin on pregnancy outcome of in vitro fertilization and embryo transfer
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摘要 目的:比较促性腺激素(gonadotropin,Gn)使用天数对体外授精-胚胎移植/卵细胞浆内单精子显微注射-胚胎移植妊娠结果的影响。方法:回顾分析2009年1月~3月我中心试管婴儿助孕治疗143例,其中IVF周期88例,ICSI周期55例。按使用Gn的天数分为两组:A组使用Gn8~13天,B组使用Gn14~19天(最长19天)。结果:两组一般情况无统计学差异;两组HCG日≥19mm卵泡、≥18mm卵泡、次日血HCG值、内膜厚度类型、胚胎质量、生化妊娠和临床妊娠均无统计学差异;而≥20mm、≥16mm、≥14mm、≥11mm卵泡数以及获卵数A组显著高于B组。结论:Gn使用天数影响获卵数,而内膜厚度类型、胚胎质量、生化妊娠以及临床妊娠率无统计学差异。 Objectives:To evaluate the impact of different duration of gonadotropin on pregnancy outcome of in vitro fertilization and intracytoplasmic sperm injection and embryo transfer.Methods:From Jan.to Mar.2009,143 fresh cycles of assisted reproductive techniques were analyzed,including 88 cycles of IVF-ET and 55 of ICSI-ET.They were divided into two groups.In group A,the duration of gonadotropin was within 8~13 days,while in group B,it lasted for 14~19 days.Results:There were no significant differences between the basic information of the two groups.And there were no obvious differences among the number of follicles with diameter ≥19mm and 18mm,endometrial thickness and pattern,quality of embryo,the biochemical and clinical pregnancy rate.But the number of follicles with diameter ≥20mm,16mm,14mm,11mm and the number of retrieved oocytes of group A were significantly higher than those of group B respectively.Conclusion:The duration of gonadotropin can affect the number of retrieved oocytes.But it has no effect on the quality of embryo,endometrial thickness and pattern,and the rate of biochemical or clinical pregnancy.
出处 《现代妇产科进展》 CSCD 北大核心 2010年第4期289-291,共3页 Progress in Obstetrics and Gynecology
关键词 促性腺激素 授精 体外 胚胎移植 妊娠率 妊娠结局 Gonadotropin Fertilization in vitro Embryo transfer Pregnancy rate Pregnancy outcome
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