摘要
通过反相高效液相色谱法研究在不同模拟水体中,溶液质量浓度、pH对盐酸环丙沙星(CPFX)在水和底泥中含量变化的影响,分析其在模拟水体中降解和残留规律。研究结果表明:在1、5、10 mg.L-1三个CPFX溶液质量浓度中,光降解度最高的溶液质量浓度为1 mg.L-1,自然光照下,72 h后盐酸环丙沙星在有底泥和无底泥的水体中残留率分别为19%和20%,光降解率与初始质量浓度成反比。在pH分别为3、5、9、11条件下,pH=9的微碱性环境下最易光降解,而当pH=3时其光稳定性最佳,48 h后水体残留率分别为22.6%和95.7%。盐酸环丙沙星进入模拟水生态系统后,水体中CPFX质量浓度迅速下降,45 d后检测不到它的存在;底泥中CPFX质量分数迅速上升,之后缓慢下降,45 d后底泥中仍有一定残留量,达到93.86μg.kg-1。
The influence of drug concentration and pH on the photodegradation of ciprofloxacin was investigated,and a reverse-phase high-performance liquid chromatographic method was developed for detecting the changes of ciprofloxacin content in water and sediments.Photodegradation of ciprofloxacin in natural light was most rapid at a concentration of 1 mg·L-1 among the three concentrations tested（1,5 and 10 mg·L-1）.After 72 h,the amounts of ciprofloxacin remaining with and without sediments were 19% and 20%,respectively.The photodegradation rate was inversely proportional to the initial drug concentration.Ciprofloxacin was most sensitive to photodegradation at pH 9 among the four pH levels tested（pH =3,5,9,11）,when the drug was in zwitterionic form.The stability increased considerably when pH=3.After 48 h,the amounts of ciprofloxacin remaining in water were 22.6 % and 95.7%,respectively.When ciprofloxacin was released into microcosms,the concentration of ciprofloxacin in water decreased rapidly,but increased concomitantly in sediments.After 45 days ciprofloxacin was undetectable in water,but a substantial concentration remained in the sediments.（approximately 93.86 μg·kg-1）.
出处
《中山大学学报（自然科学版）》
CAS
CSCD
北大核心
2010年第3期102-106,共5页
Acta Scientiarum Naturalium Universitatis Sunyatseni
基金
广东省自然科学基金资助项目(8151063201000053)
国家自然科学基金资助项目(40471118)
