摘要
常规抗肿瘤治疗包括化疗、放疗和手术治疗等方式。伴随大量抗肿瘤药物而出现的心血管毒副反应,如心功能不全、心肌缺血、高血压、血栓及心律失常等心脏毒性,受到人们越来越多的重视。面对繁多的抗肿瘤药物及其复杂的药物机理和不同的毒副反应,及时而有效的早期监测心血管系统损害情况,评估心脏收缩、舒张功能,对改善患者的长期预后和生存状况显得至关重要。抗肿瘤治疗仍在不断进步中,层出不穷的治疗方式和未知的毒副反应将成为心脏病学家和肿瘤学家需要联合面对的难题。
Routine cancer treatment employs a combination of chemotherapy,radiotherapy and surgery.Several cardiovascular complications can be induced through the use of anti-cancer agents such as cardiac insufficiency,myocardial ischemia,hypertension,thromboembolism,and arrhythmias.It is crucial for the long-term prognosis and survival of cancer patients to monitor potential cardiovascular damage and assess systolic and diastolic function that arises due to the emergence of antineoplastic agents.
出处
《心血管病学进展》
CAS
2010年第3期392-398,共7页
Advances in Cardiovascular Diseases
关键词
抗肿瘤药物
作用机理
心血管毒副反应
监测方法
治疗策略
anti-cancer agents
mechanism
cardiovascular toxicity
monitoring methods
treatment strategies
