摘要
目的了解泌尿生殖道支原体属感染状况及对抗菌药物的耐药性。方法对医院门诊可疑非淋病性尿道炎患者853例的泌尿生殖道分泌物标本,进行支原体属培养及药敏试验。结果支原体属培养阳性率59.1%,其中,解脲脲支原体（Uu）检出率最高,占77.8%;人支原体（Mh）检出率很低,仅占2.4%;Uu＋Mh感染检出率为19.8%;21-40岁年龄段患者培养阳性率最高（79.0%-79.5%）;Uu药敏试验显示：Uu对环丙沙星、氧氟沙星的耐药率为79.8%、59.9%;对普那霉素敏感率最高,为100.0%;其次对多西环素、交沙霉素、四环素敏感率较高,分别为94.9%、94.1%、93.4%。结论 Uu对喹诺酮类抗菌药物已产生了严重的耐药性,临床应限制使用。
OBJECTIVE To investigate the infection status and drug-resistance of mycoplasma and ureaplasma from genitourinary tract.METHODS Totally 853 genitourinary tract specimens from suspected outpatients with non-gonococcal urethritis were collected.And mycoplasma and ureaplasma cultivation and antibiotics susceptibility testing were performed.RESULTS The positive rate of both cultivation was 59.1%,The detection rate of Ureaplasma urealyticum（Uu） was the highest,accounted for 77.8%.That of M.hominis（Mh） was the lowest,accounted for 2.4%.That of combined infection was 19.8%.That in 21 to 40 years patients was the highest（79.0-79.5%）.The antibiotics testing in Uu showed that the highest resistance rate,79.8% and 59.9%,was to ciprofloxacin and ofloxacin,respectively.100.0% of Uu were susceptible to pristinamycin.The susceptibility rates to doxycycline,josamycin and tetracycline were 94.9%,94.1% and 93.4%,respectively.CONCLUSIONS Uu is severely resistant to quinolones and the clinical prescription of quinolones should be restricted.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2010年第9期1341-1342,共2页
Chinese Journal of Nosocomiology
关键词
泌尿生殖道
支原体属
解脲脲支原体
感染
耐药性
Genitourinary tract
Mycoplasma
Ureaplasma urealyticum
Infection
Drug-resistance
