摘要
目的研究ICU医院获得性血流感染的危险因素及其对患者预后的影响。方法回顾性分析北京中日友好医院ICU 108例医院获得性血流感染患者,评价住院病死率及其危险因素。结果 108例患者中66例死亡,病死率61.1%;经过对死亡组和生存组各项特征的单因素分析及多因素Logistic回归分析发现,血流感染时死亡组和生存组APACHEⅡ评分>18分(90.9%与19.0%)、多器官功能障碍综合征(MODS)评分>8分(83.3%与4.8%)、血流感染前肠外营养(77.3%与38.1%)和不适当的抗菌药物治疗(62.1%与14.3%)差异有统计学意义(P<0.01)。结论血流感染时APACHEⅡ评分、MODS评分、血流感染前使用肠外营养和不适当的抗菌药物治疗是影响血流感染患者住院病死率的危险因素。
OBJECTIVE To investigate the mortality and risk factors of bloodstream infections in ICU of China-Japan Friendship Hospital.METHODS The clinical data of bloodstream infection cases admitted to ICU of China-Japan Friendship Hospital in recent four years were analyzed retrospectively,including risk factors,accompanied diseases,organism species,drug sensitivity,mortality and prognosis.RESULTS The 108 cases with bloodstream infections were diagnosed in recent four years.Single factor Logistic regression analysis combined with multiple conditional Logistic regression model analysis was conducted.Compared to other risk factors,APACHEⅡ score（〉18）（90.9% vs 19%）,multiple organ dysfunction syndrome（MODS） score（〉8）（83.3% vs 4.8%）,inappropriate antibiotics（62.1% vs 14.3%） and parenteral nutrition（77.3% vs 38.1%） were markedly different between death and survival patients.CONCLUSIONS The mortality of bloodstream infection cases in ICU is high.APACHEⅡ score,MODS score,inappropriate antibiotics and parenteral nutrition are related to mortality of bloodstream infection cases.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2010年第9期1236-1237,共2页
Chinese Journal of Nosocomiology
