摘要
目的:比较参芪扶正注射液联合化疗与单纯化疗治疗非小细胞肺癌的临床疗效及不良反应。方法:60例非小细胞肺癌患者随机分为参芪扶正注射液配合化疗组(治疗组)和单纯化疗组(对照组),其中配合化疗组30例,采用紫杉醇135mg/m2+生理盐水500ml静滴3小时以上,第1天,后予顺铂25mg/m2静滴,第1-3天方案化疗,化疗时常规行预处理,化疗前3天开始静滴参芪扶正注射液250ml,1次/日,连用10天,每21天为1周期。对照组30例化疗方案同治疗组,至少2个周期后评价疗效及生存质量改善情况。结果:参芪扶正注射液配合化疗组总有效率(40.0%)较单纯化疗组(33.3%)高,但差异无统计学意义(P>0.05),但在改善患者生活质量、减轻化疗毒性方面明显优于单纯化疗组,差异有显著性(P<0.05)。结论:参芪扶正注射液联合化疗在治疗非小细胞肺癌中可提高化疗疗效,减轻化疗毒性,提高患者生活质量。
Objective：To compare the curative effect and side effect of combined treatment with Shenqifuzheng in- jection and chemotherapy with only chemotherapy for patients with non - small cell lung cancer. Methods ： Sixty pa- tients were divided randomly into two groups ,30 patients of observation group received PTX 135mg/m2 on dl and cis- platin 25mg/m2 on dl - d3 combined with Shenqifuzheng injection on dl - dl0 of every 21 days ,30 patients of control group were given only chemotherapy. All patients were treated not less than 2 cycles. Results：The overall response rates of observation group and control group were 40.0% and 33.3% respectively, there was no significant difference between two groups （P 〉 0.05 ） ; The life quality and relieved chemotherapy toxicity of patients in observation group were superior to patients in control group（ P 〈 0.05 ）. Conclusion：Shenqifuzheng injection can improve curative effect of non - small cell lung cancer , decrease toxic reaction and improve life quality of patients with NSCLC.
出处
《现代肿瘤医学》
CAS
2010年第5期925-926,共2页
Journal of Modern Oncology
关键词
参芪扶正注射液
非小细胞肺癌
化疗
Shenqifuzheng injection
non- small cell lung cancer
chemotherapy
