摘要
目的探讨吡柔吡星膀胱内灌注预防膀胱癌术后复发的疗效及安全性。方法52例膀胱癌术后患者分为两组,分别用吡柔吡星（THP组）和卡介苗（BCG组）定期膀胱内灌注,随防13-36个月,观察灌注后肿瘤复发情况及并发症。结果THP组复发率17.9%,不良反应率89.3%;BCG组复发率16.6%,不良反应率79.2%。结论吡柔吡星膀胱灌注预防膀胱癌术后复发有效率与卡介苗相同,是一种安全、有效的药物。
Objective To investigate the effect and safety of preventing carcinoma of bladder postoperative recrudescence with irrigation of bladder by perarubicin.Methods Fifty-two cases of carcinoma of bladder postoperation were divided into THP group and BCG group,each irrigated regularly with perarubicin and BCG respectively with 13-36 months follow-up.After irrigation,tumor recrudescence and complication were observed.Results The recurrence rate in THP group was 17.9%,side reaction rate was 89.3%.The recurrence rate in BCG group was 16.6%,side reaction mate was 79.2%.Conclusion For efficiency,perarubicin,as well as BCG,is a safe and effect drug on preventing carcinoma of bladder postoperative recrudescence.
出处
《临床医学》
CAS
2010年第3期27-28,共2页
Clinical Medicine
关键词
膀胱癌
吡柔吡星
膀胱灌注
Carcinoma of bladder
Perarubicin
Irrigation of bladder
