摘要
目的分析讨论脑胶质细胞增生症的病因、临床特点、病理及其演变。方法对34例脑胶质细胞增生症病例进行回顾性研究、通过长期随访和病理切片复查进行分析。结果其病因可能与颅内感染特别是隐匿性病毒感染、脑缺血缺氧、脑外伤、脑放射治疗有关;多数患者有颅内压增高表现,半数以上有癫痫发作;病理切片发现100%有不同程度的小胶质细胞增生,794%有轻度少突胶质细胞增生,205%有星形细胞增生;平均随访11年4个月,706%术后恢复良好;但有118%术后演变为间变性星形胶质细胞瘤和少突胶质细胞瘤。结论脑胶质细胞增生是良性病理改变,但有恶变的可能。
Objective To discuss the etiology, chinical characteristics, pathology and canceration in gliosis. Method 34 cases of gliosis were analyzed retrospectively followup for a long period. Their pathologic slices were restudied. Result The causes of gliosis included cranial infection, specially infection casued by virus without distiuct symptoms cerebral ischemia, brain injury, radiological treatment of brain. most cases showed symptoms of intracrainal hypertension, 559% of the patients accompanied with epilepsy. Pathological examination revealed proliferation of small gliocyts in all cases, lligodendrogliosis in 794% of the cases.The cases with proliferation had better rehabilitation. Canceration was noted in 118% of all cases. Conclusion Gliosis is a nonmalignant disease, however, it has the possibility of canceration.
出处
《中华外科杂志》
CAS
CSCD
北大核心
1998年第8期469-471,I092,共4页
Chinese Journal of Surgery