摘要
目的：探讨软骨样肌纤维母细胞肉瘤的组织学、超微结构和免疫组化特点。方法：采用光镜、电镜、组织化学及免疫组化染色，观察肿瘤形态学表现。结果：光镜下见肿瘤主要由梭形细胞和软骨样细胞组成。ＶＧ染色呈红、黄相间，Ｍａｓｓｏｎ染色瘤细胞呈蓝、红相间，免疫组化ｖｉｍｅｎｔｉｎ、α－ＳＭＡ、ｄｅｓｍｉｎ及α－ＡＴ均为阳性。超微结构，瘤细胞含有丰富的粗面内质网及数量不等的肌丝束、密体和密斑。结论：肌纤维母细胞肉瘤是一型独立的肿瘤，超微结构观察是诊断的主要依据。
Purpose To reported a case of chondroid myofibroblastosarcoma within right vastus lateral musculus and its ultrastructural, histochemical and immunohistochemical appearance were described fully. Methods By lightelectron microscopy observation and histochemicalimmunohistochemical staining, the details of the tumor was studied. Results Light microscopically, the tumor was mainly consisting of spindled and chondroid cells. Histochemistry, the red colour alternated with yellow in the tumor while in the VG staining, and the blue alternated with red in the Masson staining. Immunohistochemistry, the tumor cells were all positive for vimentin, αSMA, desmin and αAT. Ultrastructure, the tumor cells contained an abundace of rough endoplsmic reticulum and a variable number of myofilaments, dense body and dense patch. Conclusion Myofibroblastosarcoma was a type of independent soft tissue tumor. Observation of electron microscopy was a main accordance in diagnosis this tumor, histochemical and immunohistochemical staining possessed an important value of reference.
出处
《临床与实验病理学杂志》
CAS
CSCD
1998年第3期247-249,I035,共4页
Chinese Journal of Clinical and Experimental Pathology
关键词
软组织肉瘤
肌纤维母细胞病
病理学
soft tissue neoplasms
myofibroblastosarcoma
histocytochemistry
immunohistochemistry
ultrastructure
microscopy, electron
