摘要
目的对医院剖宫产患者同手术期抗菌药物的使用进行统计、分析，评价用药合理性。方法运用抽样调查法、药物利用评价和药物频度分析法对抗菌药物应用进行回顾性统计分析与评价。结果130例手术患者全部使用了抗菌药物，用药频度较高的药品是奥硝唑、头孢替安、头孢唑林；相对用药频度DDD费用最高的品种为头孢替安、五水头孢唑林、奥硝唑等；术后抗菌药物一般用药3～4d．术后无并发感染；联合用药率99．2％。结论目前存在的问题是剖宫产围手术期抗菌药物在术后的使用时间长、抗厌氧菌药物选用档次高、无指征使用三联、四联抗菌药物等；抗菌药物的使用应以《围手术期预防应用抗生素指南》为参照标准，优化抗菌药物使用。
OBJECTIVE To analze statistically the application of antibiotics used in the perioperative patients with Caesarean in our hospital, in order to evaluate the rational use of antibiotics. METHODS The antibiotics application was retrospectively analyzed using the followsing methods： sampling research method, drug using evaluation method and drug frequency analysis method. RESULTS All of the 130 Caesarean-operation patients had used antibiotics. The high frequent antibiotics applications contained ornidazole, cefotiam and eefozolin. The most expensive kinds of antibiotics included cefotiam, cefozolin pentahydrate, ornidazole, etc. With usual application between three and four days after operation, there was no concurrent infection. The ratio of combined-antibiotics was 99.2%. CONCLUSIONS The are some problems existed, shch as the course of antibiotics treatment in these patients is so long after surgery, the anti-anaerobic drugs used are so superior and the use of triple and quadruple antibiotics is without indications. The use of antibiotics should be based on Guide of Prophylactic Use of Antibi- otics During Perioperative Period as the standard, and optimize the use of antibiotics.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2010年第7期986-988,共3页
Chinese Journal of Nosocomiology
关键词
优化抗菌药物
药物利用评价
围手术期
Optimized antibiotics
Evaluate the utilization of drug
Perioperative period
