摘要
目的:探讨剖宫产围手术期短疗程使用抗生素的疗效,为临床治疗提供客观依据。方法:采用随机对照设计,选择258例峨眉山市人民医院妇产科行剖宫产术的产妇,分为A、B、C 3组,每组各86例,A组在术中断脐后使用头孢拉定,B组在术后给予头孢拉定持续2天,C组在术后给予头孢拉定持续4天,观察3组使用抗生素的疗效差异。结果:术后最高体温、术后退烧时间、术后发病率、腹部切口感染以及子宫内膜炎3组组间比较,差异有统计学意义(P<0.05),B组与C组之间比较,差异无统计学意义(P>0.05);3组消化道反应、药物性皮疹、术后白细胞数和中性粒细胞数之间比较,差异无统计学意义(P>0.05)。结论:剖宫产围手术期短疗程使用抗生素可有效预防产后感染,减少术后不良反应的发生率。
Objective： To explore the curative effect of short course of antibiotics during perioperative period of cesarean section, and provide an objective basis for clinical treatment. Methods： A randomized controlled trial was performed to select 258 women receiving cesarean section in Department of Gynecology and Obstetrics in the hospital, then the women were divided into group A, group B and group C, 86 women in each group ; the women in group A were treated with Cefradine after interrupting umbilical cord, the women in group B were treated with Cefradine for continuous two days after surgery, the women in group C were treated with Cefradine for continuous four days after surgery; the curative effects in the three groups were observed. Results： There were statistically significant differences in the highest postoperative body temperature, postoperative fever time, postoperative morbidity, the incidence rates of abdominal infection of incision and endometritis among the three groups （ P 〈 0. 05 ）, but there was no statistically significant difference between group B and group C （ P 〉 0. 05 ） ; there was no statistically significant difference in gastrointestinal reaction, drug rash, postoperative white blood cell count and neutrophil count among the three groups （ P 〉 0.05 ） . Conclusion： Short course of antibiotics during perioperative period of cesarean section can ef- fectively prevent postpartum infection and reduce the incidence rates of postoperative adverse reactions.
出处
《中国妇幼保健》
CAS
北大核心
2014年第17期2675-2677,共3页
Maternal and Child Health Care of China
基金
四川省卫生厅科研课题〔090265〕
关键词
剖宫产围手术期
短疗程
抗生素
疗效观察
Perioperative period of cesarean section
Short course
Antibiotics
Observation on curative effect
