摘要
目的:比较硫酸吗啡控释片与盐酸羟考酮控释片治疗癌症疼痛的经济效果。方法:120例晚期癌痛患者分A1组(内脏癌痛患者30例)、A2组(非内脏癌痛患者30例)、B1组(内脏癌痛患者30例)和B2组(非内脏癌痛患者30例),A1、A2组口服硫酸吗啡控释片,B1、B2组口服盐酸羟考酮控释片,治疗15d,运用药物经济学原理进行成本-效果分析。结果:A1、A2、B1、B2组有效率分别为70.00%、83.33%、96.67%、90.00%,成本-效果比分别为385.71、324.01、284.58、305.67;B1、B2组相对于A1组的增量成本-效果比分别为19.12、25.50。结论:B1组无论是疗效还是经济学分析都是最佳的。
OBJECTIVE： To compare the economic effects of MS Contin and oxycontin in treatment of cancer pain. METHODS： 120 patients with cancer pain were divided into GroupA1（30 cases）,GroupA2 （30 cases）,GroupB1 （30 cases） and GroupB2（30 cases）. GroupA1 and GroupA2 were received MS Contin via p.o. for 15 days while GroupB1 and GroupB2 oxycontin via p.o. for 15 days. Pharmacoeconomics was applied in costeffectiveness analysis. RESULTS： Effective rates of GroupA1,GroupA2,GroupB1 and GroupB2 were 70.00%,83.33%,96.67% and 90.00%. The costeffectiveness ratios were 385.71,324.01, 284.58 and 305.67,respectively.The incremental costeffectiveness ratios of GroupB1 and GroupB2 were 19.12 and 25.50,respectively as comparing with GroupA1. CONCLUSION： Therapy of GroupB1 is optimal among 4 schemes based on the curative effect or costeffectiveness analysis.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第14期1269-1271,共3页
China Pharmacy
