摘要
目的研究中国人标准诊断的代谢综合征及其各组与腔隙性脑梗死（LACI）的关系。方法373例门诊及住院腔隙性脑梗死患者为LACI组，其中男性亚组203例，女性亚组170例；278例门诊体检者为对照组，其中男性亚组140例，女性亚组138例。观察代谢综合征在LACI组中男、女性亚组和对照男、女性亚组的患病率、代谢综合征各组分水平以及代谢综合征对LACI的危险度。结果LACI组男性亚组和对照组男性亚组代谢综合征的患病率分别为38．9％和15．0％，2组差异有统计学意义（P〈0．01）。LACI组女性亚组和对照组女性亚组代谢综合征的患病率分别为45．9％和21．7％，2组差异有统计学意义（P〈0．01）。除男性空腹血浆葡萄糖外，LACI组男、女性亚组代谢综合征各组分水平与对照组同性别组间差异均有统计学意义（均P〈0．05）。代谢综合征使男性和女性LACI的发病分别增加3．25和2．65倍（P〈0．01）。结论代谢综合征与LACI关系密切，代谢综合征是LACI的重要危险因素。
Objective To study the relation between the metabolic syndrome （MS） and lacunar cerebral infarction（LACI）. Methods Three hundred seventy-three LACI patients （203 men and 170 women） who met the diagnostic criteria of the China Guideline for Cerebrovascular Disease Prevention and Treatment were enrolled. 278 control subjects （140 men and 138 women） without the clinical signs of cerebral infarction were selected by detailed case history and physical examination and CT or MRI. The prevalence and risk of MS were observed in LACI group and control. MS was defined by the modified criteria in Chinese. Results The prevalence of MS in LACI groups was 38.9% in men and 45.9% in women. The prevalence of MS was significantly high in LACI groups compared with control subjects （P 〈 0. 01 ）. The components level of MS showed significant difference between LACI groups and control subjects （P 〈 0.05）. The MS was associated with 3.25 and 2.65 fold higher risk of LACI in men and women（P 〈0.01）. Conclusions There is a close relation between MS and LACI. MS is an important risk factor of LACI.
出处
《中国医药》
2010年第5期403-405,共3页
China Medicine
关键词
代谢综合征
脑梗死
危险因素
Metabolic syndrome
Cerebral infarction
Risk factor
