摘要
目的探讨食物过敏在胃黏膜呈结节状改变患者发病中的作用机制。方法对在胃镜检查中胃黏膜表现为颗粒样改变的患者(实验组)33例和花斑样改变的患者(对照组)16例,采集外周静脉血应用定性酶免疫分析法,进行血清过敏原特异性IgE抗体定性检测及11种食物IgE的定性检测。结果胃镜下胃黏膜呈结节样改变患者血清总IgE抗体阳性率高达78.8%,高于正常对照组,差异有统计学意义,并且血清食物特异性抗体IgE阳性率高达66.7%,与对照组比较,差异有统计学意义。结论食物过敏介导的体液免疫反应异常在结节样慢性胃炎发病机制中有重要的作用。
Objective To explore the function mechanism of food allergy in gastric mucosal nodular changes.Methods Peripheral vein blood was collected from 33 cases of granular changes（experimental group）and 16 cases of spotted changes（control group）in gastric mucus in endoscopic examination.The quality enzyme immune analysis was adopted to detect in quality the specific IgE antibody of serum allergen and IgE of 11 kinds of food.Results The total positive rate of serum IgE antibody was 78.8% in the patients with gastric mucosal nodular changes under endoscopy,which was higher than that in normal control group,indicating significant statistical difference.The positive rate of food specific IgE antibody in serum was up to 66.7%,indicating significant statistical difference as compared with control group.Conclusion The abnormality of body fluid immune reaction mediated by food allergy plays the important role in the pathogenesis of chronic nodular gastritis.
出处
《世界中西医结合杂志》
2010年第3期239-240,共2页
World Journal of Integrated Traditional and Western Medicine
