摘要
目的了解烟台地区过敏性疾病的主要变应原,为过敏性疾病流行病学研究及临床诊断、治疗和预防提供重要依据。方法应用阿罗格点刺试液进行皮肤点刺试验,过敏原包括霉菌Ⅰ、杂草、玉米、屋尘螨、粉尘螨、烟曲霉、豚草、禾本科谷类、黎科、动物毛、羽毛、啤酒花、树Ⅰ、水果、小虾、羊肉、花生、鸡蛋、牛奶和鲑鱼。结果508例皮肤点刺试验,282例皮试阳性,阳性率55.51%。皮试阳性率最高的前五位的过敏原(皮试阳性率>10%)依次是屋尘螨、粉尘螨、豚草、树Ⅰ、烟曲霉。尘螨过敏原(粉尘螨和屋尘螨)皮试阳性率明显高于其他过敏原(卡方检验,P<0.01)。呼吸道过敏病和皮肤过敏性疾病常见过敏原致病的可能性更大。儿童组皮试阳性率明显高于成人组(卡方检验,P<0.01);吸人性过敏原皮试阳性率明显高于食物类过敏原(卡方检验,P<0.01)。结论烟台地区皮试阳性率最高的过敏原依次是屋尘螨、粉尘螨、豚草、树Ⅰ、烟曲霉,其中尘螨皮试阳性率明显高于其他过敏原。吸人性过敏原为常见过敏原。与成人相比,过敏原导致儿童过敏性疾病发病的可能性更大。
Objective To investigate the major allergens of allergic diseases in Yantai, so as to provide information for clinical diagnosis, treatment and prevention of allergic diseases. Methods Skin prick tests （SPTs） for 20 common allergens were conducted in 508 allergic patients. The 20 common allergens were as follows： mould mixture I, weeds, mealies, dennatophagoides ptemnyssinus（DP） , dermatophagoides farinae （DF） , aspergillus fumigatus, ragweed, gramineae cereal, chenopodiaceae, animal＇ s fur, feather, lupulus, tree pollen mixture I, fruit, shrimp, mutton, peanut, eggs, milk and salmon. Results The skin prick tests were performed in the 508 cases,282 cases were positive, with the positive rate of 55.51%. The five major allergens with the highest positive rate（ positive rate 〉 10% ）were DP, DF, ragweed, tree pollen mixture I and aspergillus fumigatus. Dennatophagoides allergens （DP and DF）had the highest positive rate （chi-square criterion, P 〈 0.01 ）. The respiratory tract allergosis and the skin allergosis were more likely caused by the common allergens than the other. The positive rate of the SPTs was much higher in the children group than the adult one（ P 〈 0.01 ）. The inhalant allergens were much higher than the food ones（ P 〈 0. 01 ）. Conclusion The five major allergens with the highest positive rate （ positive rate 〉 10% ） in Yantai are DP, DF, ragweed, tree pollen mixture I and aspergillus fumigatus. Dermatophagoides allergens （DP and DF）has the highest positive rate. The inhalant allergens are common allergens. The positive rate of the SPTs is much higher in the children group than the adult one.
出处
《临床肺科杂志》
2010年第5期647-649,共3页
Journal of Clinical Pulmonary Medicine
