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大肠癌ras P^(21)表达的定量研究 被引量:1

QUANTITATIVE STUDY OF RAS P^(21) EXPRESSION IN COLORECTAL CANCER
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摘要 目的:探讨大肠癌与rasp21表达的关系。方法:应用流式细胞术和细胞免疫荧光染色技术,对46例大肠肿瘤细胞rasP21表达进行定量分析。结果:大肠癌的rasP21表达阳性率为65.7%,癌组织的产P21表达量明显高于腺癌、移行粘膜和正常粘膜。结论:测定大肠肿瘤rasP21表达有助于大肠癌的早期诊断和治疗。 Objective: To study the relationship between colorectal cancer and ras P21 expression.Methods: The oncogene ras P21 expression in 46 cases of colorectal tumor wsa analysed quantitatively using flow cytomeny and cyto-immunofluorescence staining technique. Results: The positive rate of ras P21 expression was 65.7% in colorectal carcinomas ras p21 expression higher in colorectal adenocarcinomas than in adenomas, transitional mucosa and normal mucosa. Conctheions: Detechon of ras p21 expression in colorectal tumors may be helpful in eary diagnosis and treatment.
作者 徐亮 卢光宇
出处 《泸州医学院学报》 1998年第3期181-184,共4页 Journal of Luzhou Medical College
关键词 大肠肿瘤 RASP21 诊断 治疗 Colorectal Carcinoma ras P^(21) Diagnosis Treatment
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参考文献4

  • 1左连富,齐风英,郭建文,刘江惠.P21^(ras)在胃癌前病变和胃癌细胞表达的定量研究[J].中华病理学杂志,1994,23(3):138-140. 被引量:23
  • 2Qiang Wang M.D.,Han Gao M.D.,Yonglian Chen M.D.,Yuanhe Wang M.D.,Jin He M.D.,Chengzhi Jin M.D.. Biopathologic characteristics of DNA content in crypt cells of transitional mucosa adjacent to carcinomas of the rectum and rectosigmoid[J] 1992,Diseases of the Colon & Rectum(7):670~675 被引量:1
  • 3Felice Miller M.D.,Tomas M. Heimann M.D.,Astrid Quish M.D.,Daniel J. Pyo M.D.,Arnold Szporn M.D.,Giorgio Martinelli Ph.D.,Thomas M. Fasy M.D. Ph.D.. ras and c-myc protein expression in colorectal carcinoma[J] 1992,Diseases of the Colon & Rectum(5):430~435 被引量:1
  • 4Dr. Masaki Miyahara M.D.,Takao Saito M.D.,Kazutoshi Kaketani M.D.,Koichi Sato M.D.,Akihiko Kuwahara M.D.,Katsuhiro Shimoda M.D.,Michio Kobayashi M.D.. Clinical significance of ras p21 overexpression for patients with an advanced colorectal cancer[J] 1991,Diseases of the Colon & Rectum(12):1097~1102 被引量:1

二级参考文献1

  • 1左连富,流式细胞术样品制备技术,1991年 被引量:1

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