摘要
目的:探讨大肠癌与rasp21表达的关系。方法:应用流式细胞术和细胞免疫荧光染色技术,对46例大肠肿瘤细胞rasP21表达进行定量分析。结果:大肠癌的rasP21表达阳性率为65.7%,癌组织的产P21表达量明显高于腺癌、移行粘膜和正常粘膜。结论:测定大肠肿瘤rasP21表达有助于大肠癌的早期诊断和治疗。
Objective: To study the relationship between colorectal cancer and ras P21 expression.Methods: The oncogene ras P21 expression in 46 cases of colorectal tumor wsa analysed quantitatively using flow cytomeny and cyto-immunofluorescence staining technique. Results: The positive rate of ras P21 expression was 65.7% in colorectal carcinomas ras p21 expression higher in colorectal adenocarcinomas than in adenomas, transitional mucosa and normal mucosa. Conctheions: Detechon of ras p21 expression in colorectal tumors may be helpful in eary diagnosis and treatment.
出处
《泸州医学院学报》
1998年第3期181-184,共4页
Journal of Luzhou Medical College
关键词
大肠肿瘤
RASP21
诊断
治疗
Colorectal Carcinoma
ras P^(21)
Diagnosis
Treatment