摘要
目的通过对金黄色葡萄球菌常用抗菌药物的耐药情况的分析,指导临床合理使用抗生素。方法应用WALKAWAY-40系统分离鉴定出326株金黄色葡萄球菌并检测β-内酰胺酶阳性和耐苯唑西林的菌株。结果β-内酰胺酶阳性金黄色葡萄球菌的分离率为95.4%,对抗生素的耐药性高于β-内酰胺酶阴性菌;耐苯唑西林的金黄色葡萄球菌分离率为70.2%,除万古霉素外对其他抗生素均为高度耐药,与苯唑西林敏感金黄色葡萄球菌比较,差异具有显著性意义(P<0.05)。结论326株金黄色葡萄球菌耐药性分析,其耐药性需引起临床医师的高度关注,应根据分离株耐药特点选用不同的治疗方案。
Objective According to the resistance analysis to Staphylococcus Aureus clinical strains, we can instruct to use antibiotics in clinic properly. Methods Using the system of WALKAWAY-40, we can separate and identify 326 Staphylococcus Aureus, even though we can test the strains of β-lactamase positive rate ＆ resistance oxacillin. Result The percent of separation for β-lactamase positive rate is 95.4% and its resistance to antibiotics is higher than β-1aetamase negative rate. The percent of seperation for resistance oxaeillin Staphylococcus Aureus is 70.2%. Only vaneomycin is rather highly resistant to other antibiotics. The difference is of obvious meaning （P〈0.05）, compared with oxacillin Staphylococcus Aureus. Conclusion Resistance analysis to 326 Staphylococcus Aureus. Their resistance needs more high attention from clinic doctors. We must use different treatment protocols in accordance with resistance characteristics of isolates.
出处
《中国医药指南》
2010年第10期15-17,共3页
Guide of China Medicine
