摘要
目的评价经鼻(面)罩机械通气治疗老年慢性阻塞性肺疾病(COPD)呼吸衰竭的疗效。方法选择COPD急性加重伴Ⅱ型呼吸衰竭的60岁以上老年患者24例,在常规治疗的基础上经鼻(面)罩压力支持+通气呼气末正压(PSV+PEEP)治疗,自主呼吸减弱时改用同步间歇强制通气+压力支持(SIMV+PSV)治疗为机械通气组(治疗组),并以同期病情相当的24例患者仅采用常规治疗作对照组。动态观察两组患者治疗前后动脉血气及病情变化。结果治疗组与对照组治疗前的各项指标相仿P>0.05;治疗组通气治疗前后动脉氧分压(PaO2)及动脉二氧化碳分压(PaCO2)明显改善P<0.01;治疗48h候通气治疗组PaO2及PaCO2明显好于对照组P<0.01;通气治疗组与对照组平均住院时间分别为(15±6)和(22±11)天,P<0.05,通气治疗组平均住院时间明显缩短。结论经鼻(面)罩无创机械通气对老年COPD呼吸衰竭疗效肯定,早期应用可促进疾病康复,缩短住院时间,不失为COPD呼吸衰竭治疗的重要手段。
Objective To determine the efficacy of oro-nasal facemask mechanical ventilation （MV） in respiratory faihure induced by COPD in the elders. Methods 24 patients over sixty years old who developed COPD and Ⅱ -type respiratory faihure were involved in the study （ study group）. They received basic treatment and non-invasive mechanical ventilation （PSV ＋ PEEP）. SIMV ＋ PSV was used if the patient, s spontaneous res- pirations were inadequate. 24 patieents with equivalent disease status receive basic treatment and supplemental oxygen（ control group）. The two groups were monitored for changes in arterial blood gas. Results Both groups have the similar clinical characteristics before treatments（ P 〉 0. 05 ）. The PaO2 and PaCO2 in the study group were improved after ventiation（ P 〈 0. 01 ）. The average duration of hospital stay was 15 ± 6 days for the study group vs. 22 ±11 days for the control group（P 〈 0. 05 ）. Conclusion The efficacy of non-invasive mechanical ventilation. The early use non-invasive mechanical ventilation can shorten the recovery time and shorten duration of hospital stay.
出处
《中国实用医药》
2010年第5期20-21,共2页
China Practical Medicine
关键词
肺疾病
阻塞性
呼吸衰竭
机械通气
鼻(面)罩
Puhnonary disease
Obstructive
Respiratory faiure
Mechanical ventilation
Omnasal face mask
